Serum-Nutrient Starvation Induces Cell Death Mediated by Bax and Puma That Is Counteracted by p21 and Unmasked by Bcl-xL Inhibition

Open Access

Peer-reviewed

Research Article

Serum-Nutrient Starvation Induces Cell Death Mediated by Bax and Puma That Is Counteracted by p21 and Unmasked by Bcl-x_L Inhibition

Frédérique Braun ,

* E-mail: frederique.braun@univ-nantes.fr (FB); philippe.juin@univ-nantes.fr (PJ)

Affiliation Institut de Recherche Thérapeutique de l'Université de Nantes, Centre de Recherche en Cancérologie Nantes Angers, Institut National de la Santé et de la Recherche Médicale UMR 892/Université de Nantes, Nantes, France
⨯
Joséphine Bertin-Ciftci,

Affiliation Institut de Recherche Thérapeutique de l'Université de Nantes, Centre de Recherche en Cancérologie Nantes Angers, Institut National de la Santé et de la Recherche Médicale UMR 892/Université de Nantes, Nantes, France
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Anne-Sophie Gallouet,

Affiliation Institut de Recherche Thérapeutique de l'Université de Nantes, Centre de Recherche en Cancérologie Nantes Angers, Institut National de la Santé et de la Recherche Médicale UMR 892/Université de Nantes, Nantes, France
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Julie Millour,

Affiliation Institut de Recherche Thérapeutique de l'Université de Nantes, Centre de Recherche en Cancérologie Nantes Angers, Institut National de la Santé et de la Recherche Médicale UMR 892/Université de Nantes, Nantes, France
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Philippe Juin

* E-mail: frederique.braun@univ-nantes.fr (FB); philippe.juin@univ-nantes.fr (PJ)

Affiliation Institut de Recherche Thérapeutique de l'Université de Nantes, Centre de Recherche en Cancérologie Nantes Angers, Institut National de la Santé et de la Recherche Médicale UMR 892/Université de Nantes, Nantes, France
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Apoptosis
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Cell death
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Small interfering RNA
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Transfection
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Breast cancer
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Mitochondria
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Cancer treatment
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Colorectal cancer
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