Berberine Radiosensitizes Human Esophageal Cancer Cells by Downregulating Homologous Recombination Repair Protein RAD51

Qiao Liu; Haiyan Jiang; Zhaojian Liu; Yu Wang; Minnan Zhao; Chunyan Hao; Shuai Feng; Haiyang Guo; Bing Xu; Qifeng Yang; Yaoqin Gong; Changshun Shao

doi:10.1371/journal.pone.0023427

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Open Access

Peer-reviewed

Research Article

Berberine Radiosensitizes Human Esophageal Cancer Cells by Downregulating Homologous Recombination Repair Protein RAD51

Qiao Liu ,

Contributed equally to this work with: Qiao Liu, Haiyan Jiang

Affiliation Key Laboratory of Experimental Teratology, Ministry of Education, and Institute of Molecular Medicine and Genetics, Shandong University School of Medicine, Jinan, Shandong, China
⨯
Haiyan Jiang ,

Contributed equally to this work with: Qiao Liu, Haiyan Jiang

Affiliation Key Laboratory of Experimental Teratology, Ministry of Education, and Institute of Molecular Medicine and Genetics, Shandong University School of Medicine, Jinan, Shandong, China
⨯
Zhaojian Liu,

Affiliation Key Laboratory of Experimental Teratology, Ministry of Education, and Institute of Molecular Medicine and Genetics, Shandong University School of Medicine, Jinan, Shandong, China
⨯
Yu Wang,

Affiliation Key Laboratory of Experimental Teratology, Ministry of Education, and Institute of Molecular Medicine and Genetics, Shandong University School of Medicine, Jinan, Shandong, China
⨯
Minnan Zhao,

Affiliation Key Laboratory of Experimental Teratology, Ministry of Education, and Institute of Molecular Medicine and Genetics, Shandong University School of Medicine, Jinan, Shandong, China
⨯
Chunyan Hao,

Affiliation Department of Pathology, Qilu Hospital of Shandong University, Jinan, Shandong, China
⨯
Shuai Feng,

Affiliation Key Laboratory of Experimental Teratology, Ministry of Education, and Institute of Molecular Medicine and Genetics, Shandong University School of Medicine, Jinan, Shandong, China
⨯
Haiyang Guo,

Affiliation Key Laboratory of Experimental Teratology, Ministry of Education, and Institute of Molecular Medicine and Genetics, Shandong University School of Medicine, Jinan, Shandong, China
⨯
Bing Xu,

Affiliation Key Laboratory of Experimental Teratology, Ministry of Education, and Institute of Molecular Medicine and Genetics, Shandong University School of Medicine, Jinan, Shandong, China
⨯
Qifeng Yang,

Affiliation Department of Breast Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China
⨯
Yaoqin Gong ,

* E-mail: yxg8@sdu.edu.cn (YG); changshun.shao@gmail.com (CS)

Affiliation Key Laboratory of Experimental Teratology, Ministry of Education, and Institute of Molecular Medicine and Genetics, Shandong University School of Medicine, Jinan, Shandong, China
⨯
Changshun Shao

* E-mail: yxg8@sdu.edu.cn (YG); changshun.shao@gmail.com (CS)

Affiliation Key Laboratory of Experimental Teratology, Ministry of Education, and Institute of Molecular Medicine and Genetics, Shandong University School of Medicine, Jinan, Shandong, China
⨯

Berberine Radiosensitizes Human Esophageal Cancer Cells by Downregulating Homologous Recombination Repair Protein RAD51

Qiao Liu,
Haiyan Jiang,
Zhaojian Liu,
Yu Wang,
Minnan Zhao,
Chunyan Hao,
Shuai Feng,
Haiyang Guo,
Bing Xu,
Qifeng Yang

Published: August 8, 2011
https://doi.org/10.1371/journal.pone.0023427

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Esophageal cancer
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Lung and intrathoracic tumors
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Cytoplasmic staining
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DNA recombination
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