Critical Role of PI3K/Akt/GSK3β in Motoneuron Specification from Human Neural Stem Cells in Response to FGF2 and EGF

Luis Ojeda; Junling Gao; Kristopher G. Hooten; Enyin Wang; Jason R. Thonhoff; Tiffany J. Dunn; Tianyan Gao; Ping Wu

doi:10.1371/journal.pone.0023414

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Peer-reviewed

Research Article

Critical Role of PI3K/Akt/GSK3β in Motoneuron Specification from Human Neural Stem Cells in Response to FGF2 and EGF

Luis Ojeda ,

Contributed equally to this work with: Luis Ojeda, Junling Gao

Current address: Huffington Center on Aging, Baylor College of Medicine, Houston, Texas, United States of America

Affiliation Department of Neuroscience and Cell Biology, University Of Texas Medical Branch at Galveston, Galveston, Texas, United States of America
⨯
Junling Gao ,

Contributed equally to this work with: Luis Ojeda, Junling Gao

Affiliation Department of Neuroscience and Cell Biology, University Of Texas Medical Branch at Galveston, Galveston, Texas, United States of America
⨯
Kristopher G. Hooten,

Affiliation Department of Neurosurgery, University of Florida, Gainesville, Florida, United States of America
⨯
Enyin Wang,

Affiliations Department of Neuroscience and Cell Biology, University Of Texas Medical Branch at Galveston, Galveston, Texas, United States of America, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, Sichuan, China
⨯
Jason R. Thonhoff,

Affiliation Department of Neuroscience and Cell Biology, University Of Texas Medical Branch at Galveston, Galveston, Texas, United States of America
⨯
Tiffany J. Dunn,

Affiliation Department of Neuroscience and Cell Biology, University Of Texas Medical Branch at Galveston, Galveston, Texas, United States of America
⨯
Tianyan Gao,

Affiliation Markey Cancer Center and Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, United States of America
⨯
Ping Wu

* E-mail: piwu@utmb.edu

Affiliation Department of Neuroscience and Cell Biology, University Of Texas Medical Branch at Galveston, Galveston, Texas, United States of America
⨯

Critical Role of PI3K/Akt/GSK3β in Motoneuron Specification from Human Neural Stem Cells in Response to FGF2 and EGF

Luis Ojeda,
Junling Gao,
Kristopher G. Hooten,
Enyin Wang,
Jason R. Thonhoff,
Tiffany J. Dunn,
Tianyan Gao,
Ping Wu

Published: August 24, 2011
https://doi.org/10.1371/journal.pone.0023414

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