BAAV Mediated GJB2 Gene Transfer Restores Gap Junction Coupling in Cochlear Organotypic Cultures from Deaf Cx26Sox10Cre Mice

Giulia Crispino; Giovanni Di Pasquale; Pietro Scimemi; Laura Rodriguez; Fabian Galindo Ramirez; Romolo Daniele De Siati; Rosa Maria Santarelli; Edoardo Arslan; Mario Bortolozzi; John A. Chiorini; Fabio Mammano

doi:10.1371/journal.pone.0023279

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Open Access

Peer-reviewed

Research Article

BAAV Mediated GJB2 Gene Transfer Restores Gap Junction Coupling in Cochlear Organotypic Cultures from Deaf Cx26Sox10Cre Mice

Giulia Crispino,

Affiliations Fondazione per la Ricerca Biomedica Avanzata, Istituto Veneto di Medicina Molecolare, Padova, Italy, Dipartimento di Fisica “G. Galilei”, Università di Padova, Padova, Italy
⨯
Giovanni Di Pasquale,

Affiliation Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Pietro Scimemi,

Affiliation Dipartimento di Specialità Medico–Chirurgiche e Servizio di Audiologia, Università di Padova, Padova, Italy
⨯
Laura Rodriguez,

Affiliations Fondazione per la Ricerca Biomedica Avanzata, Istituto Veneto di Medicina Molecolare, Padova, Italy, Dipartimento di Fisica “G. Galilei”, Università di Padova, Padova, Italy
⨯
Fabian Galindo Ramirez,

Affiliation Fondazione per la Ricerca Biomedica Avanzata, Istituto Veneto di Medicina Molecolare, Padova, Italy
⨯
Romolo Daniele De Siati,

Affiliation Dipartimento di Specialità Medico–Chirurgiche e Servizio di Audiologia, Università di Padova, Padova, Italy
⨯
Rosa Maria Santarelli,

Affiliation Dipartimento di Specialità Medico–Chirurgiche e Servizio di Audiologia, Università di Padova, Padova, Italy
⨯
Edoardo Arslan,

Affiliation Dipartimento di Specialità Medico–Chirurgiche e Servizio di Audiologia, Università di Padova, Padova, Italy
⨯
Mario Bortolozzi,

Affiliations Fondazione per la Ricerca Biomedica Avanzata, Istituto Veneto di Medicina Molecolare, Padova, Italy, Dipartimento di Fisica “G. Galilei”, Università di Padova, Padova, Italy, Istituto CNR di Neuroscienze, Padova, Italy
⨯
John A. Chiorini,

Affiliation Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Fabio Mammano

* E-mail: fabio.mammano@unipd.it

Affiliations Fondazione per la Ricerca Biomedica Avanzata, Istituto Veneto di Medicina Molecolare, Padova, Italy, Dipartimento di Fisica “G. Galilei”, Università di Padova, Padova, Italy, Istituto CNR di Neuroscienze, Padova, Italy
⨯

BAAV Mediated GJB2 Gene Transfer Restores Gap Junction Coupling in Cochlear Organotypic Cultures from Deaf Cx26Sox10Cre Mice

Giulia Crispino,
Giovanni Di Pasquale,
Pietro Scimemi,
Laura Rodriguez,
Fabian Galindo Ramirez,
Romolo Daniele De Siati,
Rosa Maria Santarelli,
Edoardo Arslan,
Mario Bortolozzi,
John A. Chiorini

Published: August 18, 2011
https://doi.org/10.1371/journal.pone.0023279

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