The Kinase Inhibitor SFV785 Dislocates Dengue Virus Envelope Protein from the Replication Complex and Blocks Virus Assembly

• Azlinda Anwar ,

  * E-mail: gmsaa@nus.edu.sg (AA); hagiwara.masatoshi.8c@kyoto-u.ac.jp (MH); mariano.garciablanco@duke-nus.edu.sg (MAG-B)

  Affiliation Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore

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• Takamitsu Hosoya,

  Affiliation Laboratory of Chemical Biology, Graduate School of Biomedical Science and Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan

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• Kok Mun Leong,

  Affiliation Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore

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• Hiroshi Onogi,

  Affiliations Laboratory of Gene Expression, Graduate School of Biomedical Science and Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan, KinoPharma. Inc., Tokyo, Japan

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• Yukiko Okuno,

  Affiliation Laboratory of Gene Expression, Graduate School of Biomedical Science and Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan

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• Toshiyuki Hiramatsu,

  Affiliation Laboratory of Chemical Biology, Graduate School of Biomedical Science and Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan

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• Hiroko Koyama,

  Affiliation Division of Regeneration and Advanced Medical Science, Gifu University Graduate School of Medicine, Gifu, Japan

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• Masaaki Suzuki,

  Affiliation RIKEN Center for Molecular Imaging Science, Kobe, Japan

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• Masatoshi Hagiwara ,

  * E-mail: gmsaa@nus.edu.sg (AA); hagiwara.masatoshi.8c@kyoto-u.ac.jp (MH); mariano.garciablanco@duke-nus.edu.sg (MAG-B)

  Affiliations Laboratory of Gene Expression, Graduate School of Biomedical Science and Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan, Department of Anatomy and Developmental Biology, Kyoto University Graduate School of Medicine, Kyoto, Japan

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• Mariano A. Garcia-Blanco

  * E-mail: gmsaa@nus.edu.sg (AA); hagiwara.masatoshi.8c@kyoto-u.ac.jp (MH); mariano.garciablanco@duke-nus.edu.sg (MAG-B)

  Affiliations Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore, Center for RNA Biology, Departments of Molecular Genetics and Microbiology, and Medicine, Duke University School of Medicine, Durham, North Carolina, United States of America

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