Successful In Vitro Expansion and Differentiation of Cord Blood Derived CD34+ Cells into Early Endothelial Progenitor Cells Reveals Highly Differential Gene Expression

Ingo Ahrens; Helena Domeij; Denijal Topcic; Izhak Haviv; Ruusu-Maaria Merivirta; Alexander Agrotis; Ephraem Leitner; Jeremy B. Jowett; Christoph Bode; Martha Lappas; Karlheinz Peter

doi:10.1371/journal.pone.0023210

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Open Access

Peer-reviewed

Research Article

Successful In Vitro Expansion and Differentiation of Cord Blood Derived CD34+ Cells into Early Endothelial Progenitor Cells Reveals Highly Differential Gene Expression

Ingo Ahrens ,

Contributed equally to this work with: Ingo Ahrens, Helena Domeij

* E-mail: ingo.ahrens@uniklinik-freiburg.de

Affiliations Department of Cardiology and Angiology, University Hospital Medical Centre, Freiburg, Germany, Atherothrombosis and Vascular Biology, Baker IDI Heart and Diabetes Institute, Melbourne, Australia
⨯
Helena Domeij ,

Contributed equally to this work with: Ingo Ahrens, Helena Domeij

Affiliation Atherothrombosis and Vascular Biology, Baker IDI Heart and Diabetes Institute, Melbourne, Australia
⨯
Denijal Topcic,

Affiliation Atherothrombosis and Vascular Biology, Baker IDI Heart and Diabetes Institute, Melbourne, Australia
⨯
Izhak Haviv,

Affiliation The Blood and DNA Profiling Facility, Baker IDI Heart and Diabetes Institute, Melbourne, Australia
⨯
Ruusu-Maaria Merivirta,

Affiliation Atherothrombosis and Vascular Biology, Baker IDI Heart and Diabetes Institute, Melbourne, Australia
⨯
Alexander Agrotis,

Affiliation Department of Immunology, Alfred Medical Research and Education Precinct, Monash University, Melbourne, Australia
⨯
Ephraem Leitner,

Affiliation Atherothrombosis and Vascular Biology, Baker IDI Heart and Diabetes Institute, Melbourne, Australia
⨯
Jeremy B. Jowett,

Affiliation The Blood and DNA Profiling Facility, Baker IDI Heart and Diabetes Institute, Melbourne, Australia
⨯
Christoph Bode,

Affiliation Department of Cardiology and Angiology, University Hospital Medical Centre, Freiburg, Germany
⨯
Martha Lappas,

Affiliation Department of Obstetrics and Gynaecology, Mercy Hospital for Women, University of Melbourne, Melbourne, Australia
⨯
Karlheinz Peter

Affiliation Atherothrombosis and Vascular Biology, Baker IDI Heart and Diabetes Institute, Melbourne, Australia
⨯

Successful In Vitro Expansion and Differentiation of Cord Blood Derived CD34+ Cells into Early Endothelial Progenitor Cells Reveals Highly Differential Gene Expression

Ingo Ahrens,
Helena Domeij,
Denijal Topcic,
Izhak Haviv,
Ruusu-Maaria Merivirta,
Alexander Agrotis,
Ephraem Leitner,
Jeremy B. Jowett,
Christoph Bode,
Martha Lappas

Published: August 12, 2011
https://doi.org/10.1371/journal.pone.0023210

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Cell differentiation
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Gene expression
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Endothelial cells
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Blood
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