All Clinically-Relevant Blood Components Transmit Prion Disease following a Single Blood Transfusion: A Sheep Model of vCJD

Sandra McCutcheon; Anthony Richard Alejo Blanco; E. Fiona Houston; Christopher de Wolf; Boon Chin Tan; Antony Smith; Martin H. Groschup; Nora Hunter; Valerie S. Hornsey; Ian R. MacGregor; Christopher V. Prowse; Marc Turner; Jean C. Manson

doi:10.1371/journal.pone.0023169

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Peer-reviewed

Research Article

All Clinically-Relevant Blood Components Transmit Prion Disease following a Single Blood Transfusion: A Sheep Model of vCJD

Sandra McCutcheon ,

Contributed equally to this work with: Sandra McCutcheon, Anthony Richard Alejo Blanco, E. Fiona Houston

Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Edinburgh, United Kingdom
⨯
Anthony Richard Alejo Blanco ,

Contributed equally to this work with: Sandra McCutcheon, Anthony Richard Alejo Blanco, E. Fiona Houston

Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Edinburgh, United Kingdom
⨯
E. Fiona Houston ,

Contributed equally to this work with: Sandra McCutcheon, Anthony Richard Alejo Blanco, E. Fiona Houston

Affiliation School of Veterinary Medicine, College of Medical, Veterinary and Life Sciences, The University of Glasgow, Glasgow, United Kingdom
⨯
Christopher de Wolf,

Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Edinburgh, United Kingdom
⨯
Boon Chin Tan,

Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Edinburgh, United Kingdom
⨯
Antony Smith,

Affiliation The Institute for Animal Health, Compton, Berkshire, United Kingdom
⨯
Martin H. Groschup,

Affiliation Institute for Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Germany
⨯
Nora Hunter,

Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Edinburgh, United Kingdom
⨯
Valerie S. Hornsey,

Affiliation National Science Laboratory, Scottish National Blood Transfusion Service (SNBTS), Edinburgh, United Kingdom
⨯
Ian R. MacGregor,

Affiliation National Science Laboratory, Scottish National Blood Transfusion Service (SNBTS), Edinburgh, United Kingdom
⨯
Christopher V. Prowse,

Affiliation National Science Laboratory, Scottish National Blood Transfusion Service (SNBTS), Edinburgh, United Kingdom
⨯
Marc Turner,

Affiliation University of Edinburgh and SNBTS, Edinburgh, United Kingdom
⨯
Jean C. Manson

* E-mail: jean.manson@roslin.ed.ac.uk

Affiliation The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Edinburgh, United Kingdom
⨯

All Clinically-Relevant Blood Components Transmit Prion Disease following a Single Blood Transfusion: A Sheep Model of vCJD

Sandra McCutcheon,
Anthony Richard Alejo Blanco,
E. Fiona Houston,
Christopher de Wolf,
Boon Chin Tan,
Antony Smith,
Martin H. Groschup,
Nora Hunter,
Valerie S. Hornsey,
Ian R. MacGregor

Published: August 17, 2011
https://doi.org/10.1371/journal.pone.0023169

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