Differential Effects of TNF (TNFSF2) and IFN-γ on Intestinal Epithelial Cell Morphogenesis and Barrier Function in Three-Dimensional Culture

Kati Juuti-Uusitalo; Leon J. Klunder; Klaas A. Sjollema; Katarina Mackovicova; Ryuichi Ohgaki; Dick Hoekstra; Jan Dekker; Sven C. D. van IJzendoorn

doi:10.1371/journal.pone.0022967

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Peer-reviewed

Research Article

Differential Effects of TNF (TNFSF2) and IFN-γ on Intestinal Epithelial Cell Morphogenesis and Barrier Function in Three-Dimensional Culture

Kati Juuti-Uusitalo,

Affiliations Top Institute Food and Nutrition, Wageningen, The Netherlands, Department of Cell Biology, Section of Membrane Cell Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
⨯
Leon J. Klunder,

Affiliation Department of Cell Biology, Section of Membrane Cell Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
⨯
Klaas A. Sjollema,

Affiliations Department of Cell Biology, Section of Molecular Imaging and Electron Microscopy, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, UMCG Microscopy and Imaging Center (UMIC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
⨯
Katarina Mackovicova,

Affiliation Department of Cell Biology, Section of Membrane Cell Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
⨯
Ryuichi Ohgaki,

Affiliation Department of Cell Biology, Section of Membrane Cell Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
⨯
Dick Hoekstra,

Affiliation Department of Cell Biology, Section of Membrane Cell Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
⨯
Jan Dekker,

Current address: Department of Animal Sciences, Wageningen UR, The Netherlands

Affiliation Top Institute Food and Nutrition, Wageningen, The Netherlands
⨯
Sven C. D. van IJzendoorn

* E-mail: s.c.d.van.ijzendoorn@med.umcg.nl

Affiliations Top Institute Food and Nutrition, Wageningen, The Netherlands, Department of Cell Biology, Section of Membrane Cell Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
⨯

Differential Effects of TNF (TNFSF2) and IFN-γ on Intestinal Epithelial Cell Morphogenesis and Barrier Function in Three-Dimensional Culture

Kati Juuti-Uusitalo,
Leon J. Klunder,
Klaas A. Sjollema,
Katarina Mackovicova,
Ryuichi Ohgaki,
Dick Hoekstra,
Jan Dekker,
Sven C. D. van IJzendoorn

Published: August 11, 2011
https://doi.org/10.1371/journal.pone.0022967

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