siRNA Knockdown of Ribosomal Protein Gene RPL19 Abrogates the Aggressive Phenotype of Human Prostate Cancer

Alix Bee; Daniel Brewer; Carol Beesley; Andrew Dodson; Shiva Forootan; Timothy Dickinson; Patricia Gerard; Brian Lane; Sheng Yao; Colin S. Cooper; Mustafa B. A. Djamgoz; Christine M. Gosden; Youqiang Ke; Christopher S. Foster

doi:10.1371/journal.pone.0022672

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Open Access

Peer-reviewed

Research Article

siRNA Knockdown of Ribosomal Protein Gene RPL19 Abrogates the Aggressive Phenotype of Human Prostate Cancer

Alix Bee,

Affiliation Section of Cellular Pathology and Molecular Genetics, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯
Daniel Brewer,

Affiliation Molecular Carcinogenesis Group, Institute of Cancer Research, Sutton, Surrey, United Kingdom
⨯
Carol Beesley,

Affiliation Section of Cellular Pathology and Molecular Genetics, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯
Andrew Dodson,

Affiliation Section of Cellular Pathology and Molecular Genetics, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯
Shiva Forootan,

Affiliation Section of Cellular Pathology and Molecular Genetics, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯
Timothy Dickinson,

Affiliation Section of Cellular Pathology and Molecular Genetics, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯
Patricia Gerard,

Affiliation Section of Cellular Pathology and Molecular Genetics, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯
Brian Lane,

Affiliation Liverpool Microarray Facility, Centre for Genomic Research, University of Liverpool, Liverpool, United Kingdom
⨯
Sheng Yao,

Affiliation Section of Cellular Pathology and Molecular Genetics, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯
Colin S. Cooper,

Affiliation Molecular Carcinogenesis Group, Institute of Cancer Research, Sutton, Surrey, United Kingdom
⨯
Mustafa B. A. Djamgoz,

Affiliation Division of Cell and Molecular Biology, Imperial College London, London, United Kingdom
⨯
Christine M. Gosden,

Affiliation Section of Cellular Pathology and Molecular Genetics, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯
Youqiang Ke,

Affiliation Section of Cellular Pathology and Molecular Genetics, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯
Christopher S. Foster

* E-mail: csfoster@liv.ac.uk

Affiliation Section of Cellular Pathology and Molecular Genetics, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯

siRNA Knockdown of Ribosomal Protein Gene RPL19 Abrogates the Aggressive Phenotype of Human Prostate Cancer

Alix Bee,
Daniel Brewer,
Carol Beesley,
Andrew Dodson,
Shiva Forootan,
Timothy Dickinson,
Patricia Gerard,
Brian Lane,
Sheng Yao,
Colin S. Cooper

Published: July 22, 2011
https://doi.org/10.1371/journal.pone.0022672

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Gene expression
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Cancers and neoplasms
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Small interfering RNA
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