Requirement of Cognate CD4+ T-Cell Recognition for the Regulation of Allospecific CTL by Human CD4+CD127−CD25+FOXP3+ Cells Generated in MLR

Yuming Yu; Joshua Miller; Joseph R. Leventhal; Anat R. Tambur; Dhivya Chandrasekaran; Josh Levitsky; Xunrong Luo; James M. Mathew

doi:10.1371/journal.pone.0022450

Loading metrics

Open Access

Peer-reviewed

Research Article

Requirement of Cognate CD4⁺ T-Cell Recognition for the Regulation of Allospecific CTL by Human CD4⁺CD127⁻CD25⁺FOXP3⁺ Cells Generated in MLR

Yuming Yu,

Affiliations Department of Surgery, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Department of Organ Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China
⨯
Joshua Miller,

Affiliations Department of Surgery, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Jesse Brown VA Medical Center, Chicago, Illinois, United States of America
⨯
Joseph R. Leventhal,

Affiliation Department of Surgery, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
⨯
Anat R. Tambur,

Affiliation Department of Surgery, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
⨯
Dhivya Chandrasekaran,

Affiliation Department of Surgery, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
⨯
Josh Levitsky,

Affiliations Department of Surgery, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Division of Hepatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
⨯
Xunrong Luo,

Affiliations Department of Surgery, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Division of Nephrology and Hypertension, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
⨯
James M. Mathew

* E-mail: james-mathew@northwestern.edu

Affiliations Department of Surgery, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Jesse Brown VA Medical Center, Chicago, Illinois, United States of America, Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
⨯

Requirement of Cognate CD4⁺ T-Cell Recognition for the Regulation of Allospecific CTL by Human CD4⁺CD127⁻CD25⁺FOXP3⁺ Cells Generated in MLR

Yuming Yu,
Joshua Miller,
Joseph R. Leventhal,
Anat R. Tambur,
Dhivya Chandrasekaran,
Josh Levitsky,
Xunrong Luo,
James M. Mathew

Published: July 22, 2011
https://doi.org/10.1371/journal.pone.0022450

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cytotoxic T cells
Is the Subject Area "Cytotoxic T cells" applicable to this article?

Thanks for your feedback.
Regulatory T cells
Is the Subject Area "Regulatory T cells" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Flow cytometry
Is the Subject Area "Flow cytometry" applicable to this article?

Thanks for your feedback.
Antigen-presenting cells
Is the Subject Area "Antigen-presenting cells" applicable to this article?

Thanks for your feedback.
Intracellular membranes
Is the Subject Area "Intracellular membranes" applicable to this article?

Thanks for your feedback.
Cytotoxicity
Is the Subject Area "Cytotoxicity" applicable to this article?

Thanks for your feedback.
Organ transplantation
Is the Subject Area "Organ transplantation" applicable to this article?

Thanks for your feedback.