Comparative Analysis of mRNA Isoform Expression in Cardiac Hypertrophy and Development Reveals Multiple Post-Transcriptional Regulatory Modules

Ji Yeon Park; Wencheng Li; Dinghai Zheng; Peiyong Zhai; Yun Zhao; Takahisa Matsuda; Stephen F. Vatner; Junichi Sadoshima; Bin Tian

doi:10.1371/journal.pone.0022391

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Peer-reviewed

Research Article

Comparative Analysis of mRNA Isoform Expression in Cardiac Hypertrophy and Development Reveals Multiple Post-Transcriptional Regulatory Modules

Ji Yeon Park,

Affiliations Department of Cell Biology and Molecular Medicine, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America, New Jersey Medical School and Graduate School of Biomedical Science, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
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Wencheng Li,

Affiliation Department of Biochemistry and Molecular Biology, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
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Dinghai Zheng,

Affiliation Department of Biochemistry and Molecular Biology, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
⨯
Peiyong Zhai,

Affiliation Department of Cell Biology and Molecular Medicine, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
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Yun Zhao,

Affiliation Department of Biochemistry and Molecular Biology, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
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Takahisa Matsuda,

Affiliation Department of Cell Biology and Molecular Medicine, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
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Stephen F. Vatner,

Affiliation Department of Cell Biology and Molecular Medicine, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
⨯
Junichi Sadoshima,

Affiliation Department of Cell Biology and Molecular Medicine, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
⨯
Bin Tian

* E-mail: btian@umdnj.edu

Affiliations Department of Biochemistry and Molecular Biology, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America, New Jersey Medical School and Graduate School of Biomedical Science, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America
⨯

Comparative Analysis of mRNA Isoform Expression in Cardiac Hypertrophy and Development Reveals Multiple Post-Transcriptional Regulatory Modules

Ji Yeon Park,
Wencheng Li,
Dinghai Zheng,
Peiyong Zhai,
Yun Zhao,
Takahisa Matsuda,
Stephen F. Vatner,
Junichi Sadoshima,
Bin Tian

Published: July 22, 2011
https://doi.org/10.1371/journal.pone.0022391

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Gene regulation
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Gene expression
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Cardiac hypertrophy
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Post-transcriptional gene regulation
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MicroRNAs
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Messenger RNA
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Heart
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Microarrays
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