S100B and APP Promote a Gliocentric Shift and Impaired Neurogenesis in Down Syndrome Neural Progenitors

• Jie Lu,

  Affiliation Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

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• Giuseppe Esposito,

  Affiliation Department of Human Physiology and Pharmacology “V. Erspamer”, Faculty of Pharmacy, University of Rome “La Sapienza”, Piazzale Aldo Moro, Rome, Italy

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• Caterina Scuderi,

  Affiliation Department of Human Physiology and Pharmacology “V. Erspamer”, Faculty of Pharmacy, University of Rome “La Sapienza”, Piazzale Aldo Moro, Rome, Italy

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• Luca Steardo,

  Affiliation Department of Human Physiology and Pharmacology “V. Erspamer”, Faculty of Pharmacy, University of Rome “La Sapienza”, Piazzale Aldo Moro, Rome, Italy

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• Laurent C. Delli-Bovi,

  Affiliation Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Jonathan L. Hecht,

  Affiliation Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

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• Bryan C. Dickinson,

  Affiliation Howard Hughes Medical Institute, Department of Chemistry, University of California, Berkeley, California, United States of America

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• Christopher J. Chang,

  Affiliations Howard Hughes Medical Institute, Department of Chemistry, University of California, Berkeley, California, United States of America, Howard Hughes Medical Institute, University of California, Berkeley, California, United States of America

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• Takashi Mori,

  Affiliation Departments of Biomedical Sciences and Pathology, Saitama Medical Center and Saitama Medical University, Kawagoe, Saitama, Japan

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• Volney Sheen

  * E-mail: vsheen@bidmc.harvard.edu

  Affiliation Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

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