TRIF Is a Critical Negative Regulator of TLR Agonist Mediated Activation of Dendritic Cells In Vivo

Sergey S. Seregin; Yasser A. Aldhamen; Daniel M. Appledorn; Charles F. Aylsworth; Sarah Godbehere; Chyong-Jy Joyce Liu; Dionisia Quiroga; Andrea Amalfitano

doi:10.1371/journal.pone.0022064

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Peer-reviewed

Research Article

TRIF Is a Critical Negative Regulator of TLR Agonist Mediated Activation of Dendritic Cells In Vivo

Sergey S. Seregin ,

Contributed equally to this work with: Sergey S. Seregin, Yasser A. Aldhamen

Affiliation Department of Microbiology and Molecular Genetics, Department of Pediatrics, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, United States of America
⨯
Yasser A. Aldhamen ,

Contributed equally to this work with: Sergey S. Seregin, Yasser A. Aldhamen

Affiliation Department of Microbiology and Molecular Genetics, Department of Pediatrics, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, United States of America
⨯
Daniel M. Appledorn,

Affiliation Department of Microbiology and Molecular Genetics, Department of Pediatrics, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, United States of America
⨯
Charles F. Aylsworth,

Affiliation Department of Microbiology and Molecular Genetics, Department of Pediatrics, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, United States of America
⨯
Sarah Godbehere,

Affiliation Department of Microbiology and Molecular Genetics, Department of Pediatrics, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, United States of America
⨯
Chyong-Jy Joyce Liu,

Affiliation Department of Microbiology and Molecular Genetics, Department of Pediatrics, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, United States of America
⨯
Dionisia Quiroga,

Affiliation Department of Microbiology and Molecular Genetics, Department of Pediatrics, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, United States of America
⨯
Andrea Amalfitano

* E-mail: amalfit1@msu.edu

Affiliation Department of Microbiology and Molecular Genetics, Department of Pediatrics, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, United States of America
⨯

TRIF Is a Critical Negative Regulator of TLR Agonist Mediated Activation of Dendritic Cells In Vivo

Sergey S. Seregin,
Yasser A. Aldhamen,
Daniel M. Appledorn,
Charles F. Aylsworth,
Sarah Godbehere,
Chyong-Jy Joyce Liu,
Dionisia Quiroga,
Andrea Amalfitano

Published: July 8, 2011
https://doi.org/10.1371/journal.pone.0022064

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