Resistance to the CCR5 Inhibitor 5P12-RANTES Requires a Difficult Evolution from CCR5 to CXCR4 Coreceptor Use

• Rebecca Nedellec,

  Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

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• Mia Coetzer,

  Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

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• Michael M. Lederman,

  Affiliation Department of Medicine, Case Western Reserve University, University Hospitals/Case Medical Center, Cleveland, Ohio, United States of America

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• Robin E. Offord,

  Affiliation Mintaka Foundation for Medical Research, Geneva, Switzerland

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• Oliver Hartley,

  Affiliation Department of Structural Biology and Bioinformatics, University of Geneva, Geneva, Switzerland

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• Donald E. Mosier

  * E-mail: dmosier@scripps.edu

  Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

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