Mutant Prourokinase with Adjunctive C1-Inhibitor Is an Effective and Safer Alternative to tPA in Rat Stroke

Open Access

Peer-reviewed

Research Article

Simone Tomasi ,

* E-mail: simone.tomasi@unito.it

Affiliations Neuroscience Institute Cavalieri Ottolenghi (NICO), San Luigi Gonzaga Hospital, Orbassano, Turin, Italy, Department of Anatomy, Pharmacology and Forensic Medicine, University of Turin, Turin, Italy
⨯
Paolo Sarmientos,

Affiliation Primm s.r.l., San Raffaele Biomedical Science Park, Milan, Italy
⨯
Giada Giorda,

Affiliations Neuroscience Institute Cavalieri Ottolenghi (NICO), San Luigi Gonzaga Hospital, Orbassano, Turin, Italy, Department of Anatomy, Pharmacology and Forensic Medicine, University of Turin, Turin, Italy
⨯
Victor Gurewich,

Affiliation Vascular Research Laboratory, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America
⨯
Alessandro Vercelli

Affiliations Neuroscience Institute Cavalieri Ottolenghi (NICO), San Luigi Gonzaga Hospital, Orbassano, Turin, Italy, Department of Anatomy, Pharmacology and Forensic Medicine, University of Turin, Turin, Italy
⨯

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Hemorrhage
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Blood plasma
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Blood
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Ischemia
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Cerebral ischemia
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