Hydrogen Sulfide Protects against Chemical Hypoxia-Induced Cytotoxicity and Inflammation in HaCaT Cells through Inhibition of ROS/NF-κB/COX-2 Pathway

Chuntao Yang; Zhanli Yang; Meifen Zhang; Qi Dong; Xiuyu Wang; Aiping Lan; Fanqin Zeng; Peixi Chen; Chuhuai Wang; Jianqiang Feng

doi:10.1371/journal.pone.0021971

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Open Access

Peer-reviewed

Research Article

Hydrogen Sulfide Protects against Chemical Hypoxia-Induced Cytotoxicity and Inflammation in HaCaT Cells through Inhibition of ROS/NF-κB/COX-2 Pathway

Chuntao Yang ,

Contributed equally to this work with: Chuntao Yang, Zhanli Yang, Meifen Zhang

Affiliation Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Zhanli Yang ,

Contributed equally to this work with: Chuntao Yang, Zhanli Yang, Meifen Zhang

Affiliation Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Meifen Zhang ,

Contributed equally to this work with: Chuntao Yang, Zhanli Yang, Meifen Zhang

Affiliation School of Nursing, Sun Yat-sen University, Guangzhou, China
⨯
Qi Dong,

Affiliation Department of Physiology, Guangzhou Medical College, Guangzhou, China
⨯
Xiuyu Wang,

Affiliation Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Aiping Lan,

Affiliation Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Fanqin Zeng,

Affiliation Department of Dermatology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China
⨯
Peixi Chen,

Affiliation Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Chuhuai Wang ,

* E-mail: fengjq-sums@163.com (JF); rehab@163.com (CW)

Affiliation Department of Rehabilitation, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
⨯
Jianqiang Feng

* E-mail: fengjq-sums@163.com (JF); rehab@163.com (CW)

Affiliation Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯

Hydrogen Sulfide Protects against Chemical Hypoxia-Induced Cytotoxicity and Inflammation in HaCaT Cells through Inhibition of ROS/NF-κB/COX-2 Pathway

Chuntao Yang,
Zhanli Yang,
Meifen Zhang,
Qi Dong,
Xiuyu Wang,
Aiping Lan,
Fanqin Zeng,
Peixi Chen,
Chuhuai Wang,
Jianqiang Feng

Published: July 14, 2011
https://doi.org/10.1371/journal.pone.0021971

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