Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood

• Unnur S. Bjornsdottir ,

  Contributed equally to this work with: Unnur S. Bjornsdottir, Stephen T. Holgate

  Affiliation Department of Allergy/Clinical Immunology, University of Iceland, Reykjavík, Iceland

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• Stephen T. Holgate ,

  Contributed equally to this work with: Unnur S. Bjornsdottir, Stephen T. Holgate

  * E-mail: margot.otoole@pfizer.com (MOT); S.Holgate@soton.ac.uk (STH)

  Affiliation University of Southampton, Southampton, United Kingdom

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• Padmalatha S. Reddy,

  Affiliation Pfizer, Cambridge, Massachusetts, United States of America

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• Andrew A. Hill,

  Affiliation Pfizer, Cambridge, Massachusetts, United States of America

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• Charlotte M. McKee,

  Affiliation Wyeth Research, Cambridge, Massachusetts, United Sates of America

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• Cristina I. Csimma,

  Affiliation Wyeth Research, Cambridge, Massachusetts, United Sates of America

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• Amy A. Weaver,

  Affiliation Pfizer, Cambridge, Massachusetts, United States of America

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• Holly M. Legault,

  Affiliation Wyeth Research, Cambridge, Massachusetts, United Sates of America

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• Clayton G. Small,

  Affiliation Wyeth Research, Cambridge, Massachusetts, United Sates of America

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• Renee C. Ramsey,

  Affiliation Pfizer, Cambridge, Massachusetts, United States of America

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• Debra K. Ellis,

  Affiliation Wyeth Research, Cambridge, Massachusetts, United Sates of America

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• Conor M. Burke,

  Affiliation James Connolly Memorial Hospital, Dublin, Ireland

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• Philip J. Thompson,

  Affiliation Lung Institute of WA and Centre for Asthma, Allergy & Respiratory Research, University of Western Australia, Crawley, Australia

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• Peter H. Howarth,

  Affiliation University of Southampton, Southampton, United Kingdom

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• Andrew J. Wardlaw,

  Affiliation University of Leicester, Leicester, United Kingdom

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• Phillip G. Bardin,

  Affiliation Monash University and Medical Centre, Melbourne, Australia

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• David I. Bernstein,

  Affiliation University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

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• Louis B. Irving,

  Affiliation Royal Melbourne Hospital, Parkville, Australia

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• Geoffrey L. Chupp,

  Affiliation Yale University School of Medicine, New Haven, Connecticut, United States of America

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• George W. Bensch,

  Affiliation Bensch Clinical Research, Stockton, California, United States of America

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• Gregory W. Bensch,

  Affiliation Bensch Clinical Research, Stockton, California, United States of America

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• Jon E. Stahlman,

  Affiliation Allergy and Asthma Center, Conyers, Georgia, United States of America

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• Monroe Karetzky,

  Affiliation Newark Beth Israel Medical Center, Newark, New Jersey, United States of America

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• James W. Baker,

  Affiliation Baker Allergy, Asthma and Dermatology, Lake Oswego, Oregon, United States of America

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• Rachel L. Miller,

  Affiliation Columbia University Medical Center, New York, New York, United States of America

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• Brad H. Goodman,

  Affiliation Coastal Allergy and Asthma, Savannah, Georgia, United States of America

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• Donald G. Raible,

  Affiliation Pfizer, Cambridge, Massachusetts, United States of America

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• Samuel J. Goldman,

  Affiliation Pfizer, Cambridge, Massachusetts, United States of America

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• Douglas K. Miller,

  Affiliation Pfizer, Cambridge, Massachusetts, United States of America

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• John L. Ryan,

  Affiliation Wyeth Research, Cambridge, Massachusetts, United Sates of America

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• Andrew J. Dorner,

  Affiliation Wyeth Research, Cambridge, Massachusetts, United Sates of America

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• Frederick W. Immermann ,

  ¶These authors also contributed equally to this work.

  Affiliation Pfizer, Cambridge, Massachusetts, United States of America

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•  [ ... ],
• Margot O'Toole

  * E-mail: margot.otoole@pfizer.com (MOT); S.Holgate@soton.ac.uk (STH)

  Affiliation Pfizer, Cambridge, Massachusetts, United States of America

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