Smoking and COX-2 Functional Polymorphisms Interact to Increase the Risk of Gastric Cardia Adenocarcinoma in Chinese Population

Xue-Mei Zhang; Rong Zhong; Li Liu; Ying Wang; Ju-Xiang Yuan; Peng Wang; Chuang Sun; Zhi Zhang; Wen-Guang Song; Xiao-Ping Miao

doi:10.1371/journal.pone.0021894

Loading metrics

Open Access

Peer-reviewed

Research Article

Smoking and COX-2 Functional Polymorphisms Interact to Increase the Risk of Gastric Cardia Adenocarcinoma in Chinese Population

Xue-Mei Zhang ,

Contributed equally to this work with: Xue-Mei Zhang, Rong Zhong, Li Liu

* E-mail: miaoxp@mail.hust.edu.cn (XM); jyxuemei@gmail.com (XZ)

Affiliation Department of Molecular Biology, College of Life Sciences, Hebei United University, Tangshan, China
⨯
Rong Zhong ,

Contributed equally to this work with: Xue-Mei Zhang, Rong Zhong, Li Liu

Affiliation Ministry of Education Key Lab of Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Li Liu ,

Contributed equally to this work with: Xue-Mei Zhang, Rong Zhong, Li Liu

Affiliation Ministry of Education Key Lab of Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Ying Wang,

Affiliation Ministry of Education Key Lab of Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Ju-Xiang Yuan,

Affiliation Department of Epidemiology, College of Public Health, Hebei United University, Tangshan, China
⨯
Peng Wang,

Affiliation Ministry of Education Key Lab of Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Chuang Sun,

Affiliation Ministry of Education Key Lab of Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Zhi Zhang,

Affiliation Department of Oncology, Tangshan Gongren Hospital, Tangshan, China
⨯
Wen-Guang Song,

Affiliation Department of Oncology, Tangshan Gongren Hospital, Tangshan, China
⨯
Xiao-Ping Miao

* E-mail: miaoxp@mail.hust.edu.cn (XM); jyxuemei@gmail.com (XZ)

Affiliation Ministry of Education Key Lab of Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯

Smoking and COX-2 Functional Polymorphisms Interact to Increase the Risk of Gastric Cardia Adenocarcinoma in Chinese Population

Xue-Mei Zhang,
Rong Zhong,
Li Liu,
Ying Wang,
Ju-Xiang Yuan,
Peng Wang,
Chuang Sun,
Zhi Zhang,
Wen-Guang Song,
Xiao-Ping Miao

Published: July 14, 2011
https://doi.org/10.1371/journal.pone.0021894

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Smoking habits
Is the Subject Area "Smoking habits" applicable to this article?

Thanks for your feedback.
Haplotypes
Is the Subject Area "Haplotypes" applicable to this article?

Thanks for your feedback.
Cancer risk factors
Is the Subject Area "Cancer risk factors" applicable to this article?

Thanks for your feedback.
Single nucleotide polymorphisms
Is the Subject Area "Single nucleotide polymorphisms" applicable to this article?

Thanks for your feedback.
Gastric cancer
Is the Subject Area "Gastric cancer" applicable to this article?

Thanks for your feedback.
Variant genotypes
Is the Subject Area "Variant genotypes" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Nicotine
Is the Subject Area "Nicotine" applicable to this article?

Thanks for your feedback.