Innate Immune Responses to Bacterial Ligands in the Peripheral Human Lung – Role of Alveolar Epithelial TLR Expression and Signalling

Open Access

Peer-reviewed

Research Article

Andrew J. Thorley,

Affiliation Lung Cell Biology, Section of Pharmacology and Toxicology, National Heart and Lung Institute, Imperial College, London, United Kingdom
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Davide Grandolfo,

Affiliation Lung Cell Biology, Section of Pharmacology and Toxicology, National Heart and Lung Institute, Imperial College, London, United Kingdom
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Eric Lim,

Affiliation Department of Thoracic Surgery, Royal Brompton and Harefield NHS Trust, London, United Kingdom
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Peter Goldstraw,

Affiliation Department of Thoracic Surgery, Royal Brompton and Harefield NHS Trust, London, United Kingdom
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Alan Young,

Affiliation AstraZeneca R&D, Loughborough, United Kingdom
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Teresa D. Tetley

* E-mail: t.tetley@imperial.ac.uk

Affiliation Lung Cell Biology, Section of Pharmacology and Toxicology, National Heart and Lung Institute, Imperial College, London, United Kingdom
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Alveolar macrophages
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Toll-like receptors
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Cytokines
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Macrophages
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Immune receptor signaling
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Epithelial cells
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Epithelium
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Immune response
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