Milk Lacking α-Casein Leads to Permanent Reduction in Body Size in Mice

Andreas F. Kolb; Reinhard C. Huber; Simon G. Lillico; Ailsa Carlisle; Claire J. Robinson; Claire Neil; Linda Petrie; Dorte B. Sorensen; I. Anna S. Olsson; C. Bruce A. Whitelaw

doi:10.1371/journal.pone.0021775

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Open Access

Peer-reviewed

Research Article

Milk Lacking α-Casein Leads to Permanent Reduction in Body Size in Mice

Andreas F. Kolb ,

* E-mail: a.kolb@abdn.ac.uk

Affiliations Molecular Recognition Group, Hannah Research Institute, Ayr, United Kingdom, Nutrition and Epigenetics Group, Vascular Health Division, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, United Kingdom
⨯
Reinhard C. Huber,

Affiliations Laboratory Animal Science Group, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal, Division of Developmental Biology, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom, Danish Centre for Bioethics and Risk Assessment, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark
⨯
Simon G. Lillico,

Affiliation Division of Developmental Biology, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom
⨯
Ailsa Carlisle,

Affiliation Division of Developmental Biology, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom
⨯
Claire J. Robinson,

Affiliation Molecular Recognition Group, Hannah Research Institute, Ayr, United Kingdom
⨯
Claire Neil,

Affiliation Division of Developmental Biology, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom
⨯
Linda Petrie,

Affiliation Nutrition and Epigenetics Group, Vascular Health Division, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, United Kingdom
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Dorte B. Sorensen,

Affiliation Department of Large Animal Sciences, University of Copenhagen, Copenhagen, Denmark
⨯
I. Anna S. Olsson,

Affiliations Laboratory Animal Science Group, Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal, Danish Centre for Bioethics and Risk Assessment, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark
⨯
C. Bruce A. Whitelaw

Affiliation Division of Developmental Biology, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom
⨯

Milk Lacking α-Casein Leads to Permanent Reduction in Body Size in Mice

Andreas F. Kolb,
Reinhard C. Huber,
Simon G. Lillico,
Ailsa Carlisle,
Claire J. Robinson,
Claire Neil,
Linda Petrie,
Dorte B. Sorensen,
I. Anna S. Olsson,
C. Bruce A. Whitelaw

Published: July 18, 2011
https://doi.org/10.1371/journal.pone.0021775

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Milk
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Casein
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Heterozygosity
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Lactation
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Homozygosity
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Body weight
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Gene expression
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Polymerase chain reaction
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