Multiple Indices of Diffusion Identifies White Matter Damage in Mild Cognitive Impairment and Alzheimer’s Disease

Laurence O'Dwyer; Franck Lamberton; Arun L. W. Bokde; Michael Ewers; Yetunde O. Faluyi; Colby Tanner; Bernard Mazoyer; Des O'Neill; Máiréad Bartley; D. Rónán Collins; Tara Coughlan; David Prvulovic; Harald Hampel

doi:10.1371/journal.pone.0021745

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Open Access

Peer-reviewed

Research Article

Multiple Indices of Diffusion Identifies White Matter Damage in Mild Cognitive Impairment and Alzheimer’s Disease

Laurence O'Dwyer ,

* E-mail: larodwyer@gmail.com

Affiliation Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, Goethe University, Frankfurt, Germany
⨯
Franck Lamberton,

Affiliation Centre for Imaging-Neurosciences and Applications to Pathologies, UMR 6232, CNRS, CEA, University of Caen and Paris Descartes, Paris, France
⨯
Arun L. W. Bokde,

Affiliation Cognitive Systems Group, Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience (TCIN), Lloyd Building, Trinity College Dublin, Dublin, Ireland
⨯
Michael Ewers,

Affiliation Department of Radiology, VA Medical Center, University of California San Francisco, San Francisco, California, United States of America
⨯
Yetunde O. Faluyi,

Affiliations Liaison Psychiatry Service, Addenbrooke's Hospital, Cambridge, United Kingdom, Cambridgeshire and Peterborough NHS Foundation Trust, Cambridgeshire, United Kingdom
⨯
Colby Tanner,

Affiliation Department of Zoology, Trinity College Dublin, Dublin, Ireland
⨯
Bernard Mazoyer,

Affiliations Centre for Imaging-Neurosciences and Applications to Pathologies, UMR 6232, CNRS, CEA, University of Caen and Paris Descartes, Paris, France, Centre Hospitalier Universitaire, Caen, France, Institut Universitaire de France, Paris, France
⨯
Des O'Neill,

Affiliation Department of Medical Gerontology, Trinity College Dublin, Dublin, Ireland
⨯
Máiréad Bartley,

Affiliation Department of Medical Gerontology, Trinity College Dublin, Dublin, Ireland
⨯
D. Rónán Collins,

Affiliation Department of Medical Gerontology, Trinity College Dublin, Dublin, Ireland
⨯
Tara Coughlan,

Affiliation Department of Medical Gerontology, Trinity College Dublin, Dublin, Ireland
⨯
David Prvulovic,

Affiliation Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, Goethe University, Frankfurt, Germany
⨯
Harald Hampel

Affiliation Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, Goethe University, Frankfurt, Germany
⨯

Multiple Indices of Diffusion Identifies White Matter Damage in Mild Cognitive Impairment and Alzheimer’s Disease

Laurence O'Dwyer,
Franck Lamberton,
Arun L. W. Bokde,
Michael Ewers,
Yetunde O. Faluyi,
Colby Tanner,
Bernard Mazoyer,
Des O'Neill,
Máiréad Bartley,
D. Rónán Collins

Published: June 30, 2011
https://doi.org/10.1371/journal.pone.0021745

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Prefrontal cortex
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Microstructure
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