Clathrin- and Dynamin-Independent Endocytosis of FGFR3 – Implications for Signalling

Ellen Margrethe Haugsten; Malgorzata Zakrzewska; Andreas Brech; Sascha Pust; Sjur Olsnes; Kirsten Sandvig; Jørgen Wesche

doi:10.1371/journal.pone.0021708

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Peer-reviewed

Research Article

Clathrin- and Dynamin-Independent Endocytosis of FGFR3 – Implications for Signalling

Ellen Margrethe Haugsten,

Affiliations Centre for Cancer Biomedicine, Faculty Division Norwegian Radium Hospital, University of Oslo, Oslo, Norway, Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway
⨯
Malgorzata Zakrzewska,

Affiliations Centre for Cancer Biomedicine, Faculty Division Norwegian Radium Hospital, University of Oslo, Oslo, Norway, Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland
⨯
Andreas Brech,

Affiliations Centre for Cancer Biomedicine, Faculty Division Norwegian Radium Hospital, University of Oslo, Oslo, Norway, Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway
⨯
Sascha Pust,

Affiliations Centre for Cancer Biomedicine, Faculty Division Norwegian Radium Hospital, University of Oslo, Oslo, Norway, Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway
⨯
Sjur Olsnes,

Affiliations Centre for Cancer Biomedicine, Faculty Division Norwegian Radium Hospital, University of Oslo, Oslo, Norway, Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway
⨯
Kirsten Sandvig,

Affiliations Centre for Cancer Biomedicine, Faculty Division Norwegian Radium Hospital, University of Oslo, Oslo, Norway, Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway
⨯
Jørgen Wesche

* E-mail: Jorgen.Wesche@rr-research.no

Affiliations Centre for Cancer Biomedicine, Faculty Division Norwegian Radium Hospital, University of Oslo, Oslo, Norway, Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway
⨯

Clathrin- and Dynamin-Independent Endocytosis of FGFR3 – Implications for Signalling

Ellen Margrethe Haugsten,
Malgorzata Zakrzewska,
Andreas Brech,
Sascha Pust,
Sjur Olsnes,
Kirsten Sandvig,
Jørgen Wesche

Published: July 14, 2011
https://doi.org/10.1371/journal.pone.0021708

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Fibroblast growth factor
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Endocytosis
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Transfection
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Small interfering RNA
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Cell staining
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Heparin
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Membrane receptor signaling
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Confocal microscopy
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