Morphine Induces Expression of Platelet-Derived Growth Factor in Human Brain Microvascular Endothelial Cells: Implication for Vascular Permeability

Open Access

Peer-reviewed

Research Article

Hongxiu Wen,

Affiliation Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
⨯
Yaman Lu,

Affiliation Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
⨯
Honghong Yao ,

* E-mail: sbuch@unmc.edu (SB); hyao@unmc.edu (HY)

Affiliation Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
⨯
Shilpa Buch

* E-mail: sbuch@unmc.edu (SB); hyao@unmc.edu (HY)

Affiliation Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
⨯

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Morphine
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Opioids
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Receptor antagonist therapy
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Endothelial cells
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MAPK signaling cascades
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Transcription factors
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Drug abuse
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Vascular permeability
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