Grape Seed Proanthocyanidins Inhibit Melanoma Cell Invasiveness by Reduction of PGE2 Synthesis and Reversal of Epithelial-to-Mesenchymal Transition

Open Access

Peer-reviewed

Research Article

Grape Seed Proanthocyanidins Inhibit Melanoma Cell Invasiveness by Reduction of PGE₂ Synthesis and Reversal of Epithelial-to-Mesenchymal Transition

Mudit Vaid,

Affiliation Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
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Tripti Singh,

Affiliation Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
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Santosh K. Katiyar

* E-mail: skatiyar@uab.edu

Affiliations Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, Birmingham VA Medical Center, Birmingham, Alabama, United States of America
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Melanoma cells
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Cell migration
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Cancer cell migration
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COX-2 inhibitors
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Cancer treatment
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Skin tumors
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Transcription factors
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Biomarkers
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