Computational Analysis of the Spatiotemporal Coordination of Polarized PI3K and Rac1 Activities in Micro-Patterned Live Cells

Shaoying Lu; Tae-jin Kim; Chih-En Chen; Mingxing Ouyang; Jihye Seong; Xiaoling Liao; Yingxiao Wang

doi:10.1371/journal.pone.0021293

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Peer-reviewed

Research Article

Computational Analysis of the Spatiotemporal Coordination of Polarized PI3K and Rac1 Activities in Micro-Patterned Live Cells

Shaoying Lu ,

Contributed equally to this work with: Shaoying Lu, Tae-jin Kim

Affiliation Department of Bioengineering, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America
⨯
Tae-jin Kim ,

Contributed equally to this work with: Shaoying Lu, Tae-jin Kim

Affiliation Neuroscience Program, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America
⨯
Chih-En Chen,

Affiliation Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America
⨯
Mingxing Ouyang,

Affiliation Department of Bioengineering, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America
⨯
Jihye Seong,

Affiliation Neuroscience Program, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America
⨯
Xiaoling Liao,

Affiliations Department of Bioengineering, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America, Institute of Biomaterials and Living Cell Imaging Technology, Chongqing University of Science and Technology, Chongqing, People's Republic of China
⨯
Yingxiao Wang

* E-mail: yingxiao@illinois.edu

Affiliations Department of Bioengineering, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America, Neuroscience Program, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America, Department of Molecular and Integrative Physiology, Center of Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America
⨯

Computational Analysis of the Spatiotemporal Coordination of Polarized PI3K and Rac1 Activities in Micro-Patterned Live Cells

Shaoying Lu,
Tae-jin Kim,
Chih-En Chen,
Mingxing Ouyang,
Jihye Seong,
Xiaoling Liao,
Yingxiao Wang

Published: June 27, 2011
https://doi.org/10.1371/journal.pone.0021293

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