A Novel Anti-CEACAM5 Monoclonal Antibody, CC4, Suppresses Colorectal Tumor Growth and Enhances NK Cells-Mediated Tumor Immunity

Chaogu Zheng; Jing Feng; Di Lu; Ping Wang; Shu Xing; Jean-Luc Coll; Dongling Yang; Xiyun Yan

doi:10.1371/journal.pone.0021146

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Peer-reviewed

Research Article

A Novel Anti-CEACAM5 Monoclonal Antibody, CC4, Suppresses Colorectal Tumor Growth and Enhances NK Cells-Mediated Tumor Immunity

Chaogu Zheng ,

Contributed equally to this work with: Chaogu Zheng, Jing Feng

Affiliation National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, People's Republic of China
⨯
Jing Feng ,

Contributed equally to this work with: Chaogu Zheng, Jing Feng

* E-mail: yanxy@sun5.ibp.ac.cn (XY); fengjing@moon.ibp.ac.cn (JF)

Affiliation National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, People's Republic of China
⨯
Di Lu,

Affiliation National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, People's Republic of China
⨯
Ping Wang,

Affiliation National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, People's Republic of China
⨯
Shu Xing,

Affiliation National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, People's Republic of China
⨯
Jean-Luc Coll,

Affiliation Groupe de Recherche sur le Cancer du Poumon, Equipe INSERM 9924, Institut Albert Bonniot, Grenoble, France
⨯
Dongling Yang,

Affiliation National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, People's Republic of China
⨯
Xiyun Yan

* E-mail: yanxy@sun5.ibp.ac.cn (XY); fengjing@moon.ibp.ac.cn (JF)

Affiliation National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, People's Republic of China
⨯

A Novel Anti-CEACAM5 Monoclonal Antibody, CC4, Suppresses Colorectal Tumor Growth and Enhances NK Cells-Mediated Tumor Immunity

Chaogu Zheng,
Jing Feng,
Di Lu,
Ping Wang,
Shu Xing,
Jean-Luc Coll,
Dongling Yang,
Xiyun Yan

Published: June 22, 2011
https://doi.org/10.1371/journal.pone.0021146

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