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Open Access

Peer-reviewed

Research Article

Characterization of 9-Nitrocamptothecin Liposomes: Anticancer Properties and Mechanisms on Hepatocellular Carcinoma In Vitro and In Vivo

Shunzhen Zheng,

Affiliation Department of General Surgery, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, People's Republic of China
⨯
Shuang Chang,

Affiliation National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, People's Republic of China
⨯
Jinli Lu,

Affiliation Department of General Surgery, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, People's Republic of China
⨯
Zhihui Chen,

Affiliation Department of General Surgery, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, People's Republic of China
⨯
Li Xie,

Affiliation National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, People's Republic of China
⨯
Yu Nie,

Affiliation National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, People's Republic of China
⨯
Bin He,

Affiliation National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, People's Republic of China
⨯
Shengquan Zou ,

* E-mail: sqzou05@yahoo.com.cn (SZ); zwgu@scu.edu.cn (ZG)

Affiliation Department of General Surgery, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, People's Republic of China
⨯
Zhongwei Gu

* E-mail: sqzou05@yahoo.com.cn (SZ); zwgu@scu.edu.cn (ZG)

Affiliation National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, People's Republic of China
⨯

Characterization of 9-Nitrocamptothecin Liposomes: Anticancer Properties and Mechanisms on Hepatocellular Carcinoma In Vitro and In Vivo

Shunzhen Zheng,
Shuang Chang,
Jinli Lu,
Zhihui Chen,
Li Xie,
Yu Nie,
Bin He,
Shengquan Zou,
Zhongwei Gu

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Published: June 9, 2011
https://doi.org/10.1371/journal.pone.0021064

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Hepatocellular carcinoma
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Liposomes
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Apoptosis
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Cell cycle and cell division
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Cyclins
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Cancer treatment
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Adverse reactions
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Protein expression
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