A Ribosomal Misincorporation of Lys for Arg in Human Triosephosphate Isomerase Expressed in Escherichia coli Gives Rise to Two Protein Populations

Beatriz Aguirre; Miguel Costas; Nallely Cabrera; Guillermo Mendoza-Hernández; Donald L. Helseth Jr.; Paulette Fernández; Marietta Tuena de Gómez-Puyou; Ruy Pérez-Montfort; Alfredo Torres-Larios; Armando Gómez Puyou

doi:10.1371/journal.pone.0021035

Loading metrics

Open Access

Peer-reviewed

Research Article

A Ribosomal Misincorporation of Lys for Arg in Human Triosephosphate Isomerase Expressed in Escherichia coli Gives Rise to Two Protein Populations

Beatriz Aguirre,

Affiliation Departamento de Bioquímica y Biología Estructural, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico
⨯
Miguel Costas,

Affiliation Laboratorio de Biofisicoquímica, Departamento de Fisicoquímica, Facultad de Química, Universidad Nacional Autónoma de México, Mexico City, Mexico
⨯
Nallely Cabrera,

Affiliation Departamento de Bioquímica y Biología Estructural, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico
⨯
Guillermo Mendoza-Hernández,

Affiliation Departamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico
⨯
Donald L. Helseth Jr.,

Affiliation CBC/RRC Proteomic and Informatic Services, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Paulette Fernández,

Affiliation Departamento de Bioquímica y Biología Estructural, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico
⨯
Marietta Tuena de Gómez-Puyou,

Affiliation Departamento de Bioquímica y Biología Estructural, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico
⨯
Ruy Pérez-Montfort,

Affiliation Departamento de Bioquímica y Biología Estructural, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico
⨯
Alfredo Torres-Larios ,

* E-mail: torres@ifc.unam.mx (AT-L); apuyou@ifc.unam.mx (AGP)

Affiliation Departamento de Bioquímica y Biología Estructural, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico
⨯
Armando Gómez Puyou

* E-mail: torres@ifc.unam.mx (AT-L); apuyou@ifc.unam.mx (AGP)

Affiliation Departamento de Bioquímica y Biología Estructural, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico
⨯

A Ribosomal Misincorporation of Lys for Arg in Human Triosephosphate Isomerase Expressed in Escherichia coli Gives Rise to Two Protein Populations

Beatriz Aguirre,
Miguel Costas,
Nallely Cabrera,
Guillermo Mendoza-Hernández,
Donald L. Helseth Jr.,
Paulette Fernández,
Marietta Tuena de Gómez-Puyou,
Ruy Pérez-Montfort,
Alfredo Torres-Larios,
Armando Gómez Puyou

Published: June 28, 2011
https://doi.org/10.1371/journal.pone.0021035

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Urea
Is the Subject Area "Urea" applicable to this article?

Thanks for your feedback.
Monomers
Is the Subject Area "Monomers" applicable to this article?

Thanks for your feedback.
Enzymes
Is the Subject Area "Enzymes" applicable to this article?

Thanks for your feedback.
Proteases
Is the Subject Area "Proteases" applicable to this article?

Thanks for your feedback.
Transfer RNA
Is the Subject Area "Transfer RNA" applicable to this article?

Thanks for your feedback.
Database searching
Is the Subject Area "Database searching" applicable to this article?

Thanks for your feedback.
Molecular mass
Is the Subject Area "Molecular mass" applicable to this article?

Thanks for your feedback.
Size-exclusion chromatography
Is the Subject Area "Size-exclusion chromatography" applicable to this article?

Thanks for your feedback.