Social Isolation-Induced Aggression Potentiates Anxiety and Depressive-Like Behavior in Male Mice Subjected to Unpredictable Chronic Mild Stress

Xian-cang Ma; Dong Jiang; Wen-hui Jiang; Fen Wang; Min Jia; Jin Wu; Kenji Hashimoto; Yong-hui Dang; Cheng-ge Gao

doi:10.1371/journal.pone.0020955

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Peer-reviewed

Research Article

Social Isolation-Induced Aggression Potentiates Anxiety and Depressive-Like Behavior in Male Mice Subjected to Unpredictable Chronic Mild Stress

Xian-cang Ma ,

Contributed equally to this work with: Xian-cang Ma, Dong Jiang

Affiliation Department of Psychiatry, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xian, China
⨯
Dong Jiang ,

Contributed equally to this work with: Xian-cang Ma, Dong Jiang

Affiliation Department of Psychiatry, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xian, China
⨯
Wen-hui Jiang,

Affiliation Department of Psychiatry, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xian, China
⨯
Fen Wang,

Affiliation Department of Psychiatry, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xian, China
⨯
Min Jia,

Affiliation Department of Psychiatry, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xian, China
⨯
Jin Wu,

Affiliation Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan
⨯
Kenji Hashimoto,

Affiliations Department of Psychiatry, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xian, China, Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan
⨯
Yong-hui Dang ,

* E-mail: yaogaow@163.com (CGG); psydyh@mail.xjtu.edu.cn (YHD)

Affiliation Key Laboratory of Environment and Genes Related to Diseases of the Education Ministry, Key Laboratory of the Health Ministry for Forensic Medicine, Department of Forensic Medicine, Xi'an Jiaotong University School of Medicine, Xi'an, China
⨯
Cheng-ge Gao

* E-mail: yaogaow@163.com (CGG); psydyh@mail.xjtu.edu.cn (YHD)

Affiliation Department of Psychiatry, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xian, China
⨯

Social Isolation-Induced Aggression Potentiates Anxiety and Depressive-Like Behavior in Male Mice Subjected to Unpredictable Chronic Mild Stress

Xian-cang Ma,
Dong Jiang,
Wen-hui Jiang,
Fen Wang,
Min Jia,
Jin Wu,
Kenji Hashimoto,
Yong-hui Dang,
Cheng-ge Gao

Published: June 17, 2011
https://doi.org/10.1371/journal.pone.0020955

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