Anti-Malarial Drug Artesunate Attenuates Experimental Allergic Asthma via Inhibition of the Phosphoinositide 3-Kinase/Akt Pathway

Chang Cheng; W. Eugene Ho; Fera Y. Goh; Shou Ping Guan; Li Ren Kong; Wen-Qi Lai; Bernard P. Leung; W. S. Fred Wong

doi:10.1371/journal.pone.0020932

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Peer-reviewed

Research Article

Anti-Malarial Drug Artesunate Attenuates Experimental Allergic Asthma via Inhibition of the Phosphoinositide 3-Kinase/Akt Pathway

Chang Cheng,

Affiliations Departments of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, Singapore, Singapore, Immunology Program, Life Science Institute; National University of Singapore, Singapore
⨯
W. Eugene Ho,

Affiliations Departments of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, Singapore, Singapore, Immunology Program, Life Science Institute; National University of Singapore, Singapore
⨯
Fera Y. Goh,

Affiliations Departments of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, Singapore, Singapore, Immunology Program, Life Science Institute; National University of Singapore, Singapore
⨯
Shou Ping Guan,

Affiliations Departments of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, Singapore, Singapore, Immunology Program, Life Science Institute; National University of Singapore, Singapore
⨯
Li Ren Kong,

Affiliation Departments of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, Singapore, Singapore
⨯
Wen-Qi Lai,

Affiliation Departments of Physiology, Yong Loo Lin School of Medicine, National University Health System, Singapore, Singapore
⨯
Bernard P. Leung,

Affiliation Departments of Physiology, Yong Loo Lin School of Medicine, National University Health System, Singapore, Singapore
⨯
W. S. Fred Wong

* E-mail: phcwongf@nus.edu.sg

Affiliations Departments of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, Singapore, Singapore, Immunology Program, Life Science Institute; National University of Singapore, Singapore
⨯

Anti-Malarial Drug Artesunate Attenuates Experimental Allergic Asthma via Inhibition of the Phosphoinositide 3-Kinase/Akt Pathway

Chang Cheng,
W. Eugene Ho,
Fera Y. Goh,
Shou Ping Guan,
Li Ren Kong,
Wen-Qi Lai,
Bernard P. Leung,
W. S. Fred Wong

Published: June 9, 2011
https://doi.org/10.1371/journal.pone.0020932

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