Francisella tularensis 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase: Kinetic Characterization and Phosphoregulation

Arthur Tsang; Heather Seidle; Safdar Jawaid; Weidong Zhou; Clint Smith; Robin D. Couch

doi:10.1371/journal.pone.0020884

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Research Article

Francisella tularensis 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase: Kinetic Characterization and Phosphoregulation

Arthur Tsang,

Affiliations Department of Chemistry and Biochemistry, George Mason University, Manassas, Virginia, United States of America, National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, United States of America
⨯
Heather Seidle,

Affiliations Department of Chemistry and Biochemistry, George Mason University, Manassas, Virginia, United States of America, National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, United States of America
⨯
Safdar Jawaid,

Affiliations Department of Chemistry and Biochemistry, George Mason University, Manassas, Virginia, United States of America, National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, United States of America
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Weidong Zhou,

Affiliations Department of Molecular and Microbiology, George Mason University, Manassas, Virginia, United States of America, Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, Virginia, United States of America
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Clint Smith,

Affiliation Geospatial Research and Engineering Division, U.S. Army Engineer Research and Development Center, Alexandria, Virginia, United States of America
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Robin D. Couch

* E-mail: rcouch@gmu.edu

Affiliations Department of Chemistry and Biochemistry, George Mason University, Manassas, Virginia, United States of America, National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, United States of America
⨯

Francisella tularensis 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase: Kinetic Characterization and Phosphoregulation

Arthur Tsang,
Heather Seidle,
Safdar Jawaid,
Weidong Zhou,
Clint Smith,
Robin D. Couch

Published: June 9, 2011
https://doi.org/10.1371/journal.pone.0020884

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Francisella tularensis
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Enzyme assays
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Polymerase chain reaction
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Enzyme metabolism
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Phosphorylation
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Protein expression
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