Mammalian Target of Rapamycin Is a Therapeutic Target for Murine Ovarian Endometrioid Adenocarcinomas with Dysregulated Wnt/β-Catenin and PTEN

Pradeep S. Tanwar; LiHua Zhang; Tomoko Kaneko-Tarui; Michael D. Curley; Makoto M. Taketo; Poonam Rani; Drucilla J. Roberts; Jose M. Teixeira

doi:10.1371/journal.pone.0020715

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Research Article

Mammalian Target of Rapamycin Is a Therapeutic Target for Murine Ovarian Endometrioid Adenocarcinomas with Dysregulated Wnt/β-Catenin and PTEN

Pradeep S. Tanwar,

Affiliation Vincent Center for Reproductive Biology, Department of Obstetrics, Gynecology, and Reproductive Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
LiHua Zhang,

Affiliation Vincent Center for Reproductive Biology, Department of Obstetrics, Gynecology, and Reproductive Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Tomoko Kaneko-Tarui,

Affiliation Vincent Center for Reproductive Biology, Department of Obstetrics, Gynecology, and Reproductive Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Michael D. Curley,

Affiliation Vincent Center for Reproductive Biology, Department of Obstetrics, Gynecology, and Reproductive Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Makoto M. Taketo,

Affiliation Department of Pharmacology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
⨯
Poonam Rani,

Affiliation Vincent Center for Reproductive Biology, Department of Obstetrics, Gynecology, and Reproductive Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Drucilla J. Roberts,

Affiliation Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Jose M. Teixeira

* E-mail: teixeira@helix.mgh.harvard.edu

Affiliation Vincent Center for Reproductive Biology, Department of Obstetrics, Gynecology, and Reproductive Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
⨯

Mammalian Target of Rapamycin Is a Therapeutic Target for Murine Ovarian Endometrioid Adenocarcinomas with Dysregulated Wnt/β-Catenin and PTEN

Pradeep S. Tanwar,
LiHua Zhang,
Tomoko Kaneko-Tarui,
Michael D. Curley,
Makoto M. Taketo,
Poonam Rani,
Drucilla J. Roberts,
Jose M. Teixeira

Published: June 9, 2011
https://doi.org/10.1371/journal.pone.0020715

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