A Small Peptide Modeled after the NRAGE Repeat Domain Inhibits XIAP-TAB1-TAK1 Signaling for NF-κB Activation and Apoptosis in P19 Cells

Jennifer A. Rochira; Nicholas N. Matluk; Tamara L. Adams; Aldona A. Karaczyn; Leif Oxburgh; Samuel T. Hess; Joseph M. Verdi

doi:10.1371/journal.pone.0020659

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Research Article

A Small Peptide Modeled after the NRAGE Repeat Domain Inhibits XIAP-TAB1-TAK1 Signaling for NF-κB Activation and Apoptosis in P19 Cells

Jennifer A. Rochira,

Current address: Division of Cardiology, Cardiovascular Research Center, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America

Affiliations IGERT Functional Genomics Ph.D. Program, University of Maine, Orono, Maine, United States of America, Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine, United States of America, Department of Physics and Astronomy, University of Maine, Orono, Maine, United States of America
⨯
Nicholas N. Matluk,

Affiliations Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine, United States of America, Graduate School of Biomedical Sciences, University of Maine, Orono, Maine, United States of America
⨯
Tamara L. Adams,

Affiliation Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine, United States of America
⨯
Aldona A. Karaczyn,

Affiliation Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine, United States of America
⨯
Leif Oxburgh,

Affiliation Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine, United States of America
⨯
Samuel T. Hess,

Affiliation Department of Physics and Astronomy, University of Maine, Orono, Maine, United States of America
⨯
Joseph M. Verdi

* E-mail: verdij@mmc.org

Affiliation Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine, United States of America
⨯

A Small Peptide Modeled after the NRAGE Repeat Domain Inhibits XIAP-TAB1-TAK1 Signaling for NF-κB Activation and Apoptosis in P19 Cells

Jennifer A. Rochira,
Nicholas N. Matluk,
Tamara L. Adams,
Aldona A. Karaczyn,
Leif Oxburgh,
Samuel T. Hess,
Joseph M. Verdi

Published: July 18, 2011
https://doi.org/10.1371/journal.pone.0020659

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