Microsatellite Instability in Pediatric High Grade Glioma Is Associated with Genomic Profile and Differential Target Gene Inactivation

• Marta Viana-Pereira,

  Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, Section of Paediatric Oncology, Institute of Cancer Research, Sutton, Surrey, United Kingdom

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• Alicia Lee,

  Affiliation Section of Paediatric Oncology, Institute of Cancer Research, Sutton, Surrey, United Kingdom

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• Sergey Popov,

  Affiliations Section of Paediatric Oncology, Institute of Cancer Research, Sutton, Surrey, United Kingdom, Paediatric Oncology, Royal Marsden Hospital, Sutton, Surrey, United Kingdom

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• Dorine A. Bax,

  Affiliation Section of Paediatric Oncology, Institute of Cancer Research, Sutton, Surrey, United Kingdom

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• Safa Al-Sarraj,

  Affiliation Department of Clinical Neuropathology, Kings College Hospital, London, United Kingdom

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• Leslie R. Bridges,

  Affiliation Neuropathology, St George's Hospital, London, United Kingdom

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• João N. Stávale,

  Affiliation Department of Pathology, Federal University of São Paulo, São Paulo, Brazil

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• Darren Hargrave,

  Affiliation Paediatric Oncology, Royal Marsden Hospital, Sutton, Surrey, United Kingdom

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• Chris Jones ,

  * E-mail: rreis@ecsaude.uminho.pt (RMR); chris.jones@icr.ac.uk (CJ)

  Affiliations Section of Paediatric Oncology, Institute of Cancer Research, Sutton, Surrey, United Kingdom, Paediatric Oncology, Royal Marsden Hospital, Sutton, Surrey, United Kingdom

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• Rui M. Reis

  * E-mail: rreis@ecsaude.uminho.pt (RMR); chris.jones@icr.ac.uk (CJ)

  Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, Brazil

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