The Congenital Cataract-Linked G61C Mutation Destabilizes γD-Crystallin and Promotes Non-Native Aggregation

• Wang Zhang ,

  Contributed equally to this work with: Wang Zhang, Hong-Chen Cai, Fei-Feng Li

  Affiliation State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Life Sciences, Tsinghua University, Beijing, China

  ⨯
• Hong-Chen Cai ,

  Contributed equally to this work with: Wang Zhang, Hong-Chen Cai, Fei-Feng Li

  Affiliation State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Life Sciences, Tsinghua University, Beijing, China

  ⨯
• Fei-Feng Li ,

  Contributed equally to this work with: Wang Zhang, Hong-Chen Cai, Fei-Feng Li

  Current address: Genomics Research Center, Harbin Medical University, Harbin, China

  Affiliations Department of Genetics, National Research Institute for Family Planning, Beijing, China, Peking Union Medical College, Tsinghua University, Beijing, China

  ⨯
• Yi-Bo Xi,

  Affiliations State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Life Sciences, Tsinghua University, Beijing, China, Institute of Biophysics, Lanzhou University, Lanzhou, China

  ⨯
• Xu Ma ,

  * E-mail: genetic@263.net.cn (XM); ybyan@tsinghua.edu.cn (YBY)

  Affiliations Department of Genetics, National Research Institute for Family Planning, Beijing, China, Peking Union Medical College, Tsinghua University, Beijing, China

  ⨯
• Yong-Bin Yan

  * E-mail: genetic@263.net.cn (XM); ybyan@tsinghua.edu.cn (YBY)

  Affiliation State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Life Sciences, Tsinghua University, Beijing, China

  ⨯