Bcl-xL Blocks a Mitochondrial Inner Membrane Channel and Prevents Ca2+ Overload-Mediated Cell Death

Open Access

Peer-reviewed

Research Article

Bcl-x_L Blocks a Mitochondrial Inner Membrane Channel and Prevents Ca²⁺ Overload-Mediated Cell Death

Daniel Tornero,

Affiliations Unidad Asociada Neurodeath, Universidad de Castilla-La Mancha, Albacete, Spain, Laboratorio de Inmunobiología Molecular, Hospital General Universitario Gregorio Marañón, Madrid, Spain
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Inmaculada Posadas,

Affiliations Unidad Asociada Neurodeath, Universidad de Castilla-La Mancha, Albacete, Spain, Centro de Investigación Biomédica En Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain
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Valentín Ceña

* E-mail: valentin.cena@uclm.es

Affiliations Unidad Asociada Neurodeath, Universidad de Castilla-La Mancha, Albacete, Spain, Centro de Investigación Biomédica En Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain
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Mitochondria
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Apoptosis
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Cell death
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Toxicity
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Membrane potential
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Fluorescence
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MTT assay
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Free radicals
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