p21WAF1/CIP1 Upregulation through the Stress Granule-Associated Protein CUGBP1 Confers Resistance to Bortezomib-Mediated Apoptosis

Cristina Gareau; Marie-Josée Fournier; Christine Filion; Laetitia Coudert; David Martel; Yves Labelle; Rachid Mazroui

doi:10.1371/journal.pone.0020254

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Open Access

Peer-reviewed

Research Article

p21^WAF1/CIP1 Upregulation through the Stress Granule-Associated Protein CUGBP1 Confers Resistance to Bortezomib-Mediated Apoptosis

Cristina Gareau,

Affiliation Department of Molecular Biology, Medical Biochemistry, and Pathology, Faculty of Medicine, Laval University, CHUQ Research Centre/St-François d'Assise Research Centre (CRCHUQ/CRSFA), Quebec, Canada
⨯
Marie-Josée Fournier,

Affiliation Department of Molecular Biology, Medical Biochemistry, and Pathology, Faculty of Medicine, Laval University, CHUQ Research Centre/St-François d'Assise Research Centre (CRCHUQ/CRSFA), Quebec, Canada
⨯
Christine Filion,

Affiliation Department of Molecular Biology, Medical Biochemistry, and Pathology, Faculty of Medicine, Laval University, CHUQ Research Centre/St-François d'Assise Research Centre (CRCHUQ/CRSFA), Quebec, Canada
⨯
Laetitia Coudert,

Affiliation Department of Molecular Biology, Medical Biochemistry, and Pathology, Faculty of Medicine, Laval University, CHUQ Research Centre/St-François d'Assise Research Centre (CRCHUQ/CRSFA), Quebec, Canada
⨯
David Martel,

Affiliation Department of Molecular Biology, Medical Biochemistry, and Pathology, Faculty of Medicine, Laval University, CHUQ Research Centre/St-François d'Assise Research Centre (CRCHUQ/CRSFA), Quebec, Canada
⨯
Yves Labelle,

Affiliation Department of Molecular Biology, Medical Biochemistry, and Pathology, Faculty of Medicine, Laval University, CHUQ Research Centre/St-François d'Assise Research Centre (CRCHUQ/CRSFA), Quebec, Canada
⨯
Rachid Mazroui

* E-mail: rachid.mazroui@crsfa.ulaval.ca

Affiliation Department of Molecular Biology, Medical Biochemistry, and Pathology, Faculty of Medicine, Laval University, CHUQ Research Centre/St-François d'Assise Research Centre (CRCHUQ/CRSFA), Quebec, Canada
⨯

p21^WAF1/CIP1 Upregulation through the Stress Granule-Associated Protein CUGBP1 Confers Resistance to Bortezomib-Mediated Apoptosis

Cristina Gareau,
Marie-Josée Fournier,
Christine Filion,
Laetitia Coudert,
David Martel,
Yves Labelle,
Rachid Mazroui

Published: May 26, 2011
https://doi.org/10.1371/journal.pone.0020254

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