Unfaithful Maintenance of Methylation Imprints Due to Loss of Maternal Nuclear Dnmt1 during Somatic Cell Nuclear Transfer

Yanchang Wei; Yanjun Huan; Yongqian Shi; Zhongfeng Liu; Gerelchimeg Bou; Yibo Luo; Li Zhang; Cairong Yang; Qingran Kong; Jiangtian Tian; Ping Xia; Qing-Yuan Sun; ZhongHua Liu

doi:10.1371/journal.pone.0020154

Loading metrics

Open Access

Peer-reviewed

Research Article

Unfaithful Maintenance of Methylation Imprints Due to Loss of Maternal Nuclear Dnmt1 during Somatic Cell Nuclear Transfer

Yanchang Wei,

Affiliations College of Life Science, Northeast Agricultural University of China, Harbin, China, State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
⨯
Yanjun Huan,

Affiliation College of Life Science, Northeast Agricultural University of China, Harbin, China
⨯
Yongqian Shi,

Affiliation College of Life Science, Northeast Agricultural University of China, Harbin, China
⨯
Zhongfeng Liu,

Affiliation College of Life Science, Northeast Agricultural University of China, Harbin, China
⨯
Gerelchimeg Bou,

Affiliation College of Life Science, Northeast Agricultural University of China, Harbin, China
⨯
Yibo Luo,

Affiliation College of Life Science, Northeast Agricultural University of China, Harbin, China
⨯
Li Zhang,

Affiliation College of Life Science, Northeast Agricultural University of China, Harbin, China
⨯
Cairong Yang,

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
⨯
Qingran Kong,

Affiliation College of Life Science, Northeast Agricultural University of China, Harbin, China
⨯
Jiangtian Tian,

Affiliation College of Life Science, Northeast Agricultural University of China, Harbin, China
⨯
Ping Xia,

Affiliation Department of Obstetrics and Gynecology, School of Medicine, University of California Davis, Sacramento, California, United States of America
⨯
Qing-Yuan Sun ,

* E-mail: sunqy@ioz.ac.cn (Q-YS); liu086@yahoo.com (ZL)

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
⨯
ZhongHua Liu

* E-mail: sunqy@ioz.ac.cn (Q-YS); liu086@yahoo.com (ZL)

Affiliation College of Life Science, Northeast Agricultural University of China, Harbin, China
⨯

Unfaithful Maintenance of Methylation Imprints Due to Loss of Maternal Nuclear Dnmt1 during Somatic Cell Nuclear Transfer

Yanchang Wei,
Yanjun Huan,
Yongqian Shi,
Zhongfeng Liu,
Gerelchimeg Bou,
Yibo Luo,
Li Zhang,
Cairong Yang,
Qingran Kong,
Jiangtian Tian

Published: May 20, 2011
https://doi.org/10.1371/journal.pone.0020154

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

DNA methylation
Is the Subject Area "DNA methylation" applicable to this article?

Thanks for your feedback.
Oocytes
Is the Subject Area "Oocytes" applicable to this article?

Thanks for your feedback.
Embryos
Is the Subject Area "Embryos" applicable to this article?

Thanks for your feedback.
Methylation
Is the Subject Area "Methylation" applicable to this article?

Thanks for your feedback.
Genomic imprinting
Is the Subject Area "Genomic imprinting" applicable to this article?

Thanks for your feedback.
Cloning
Is the Subject Area "Cloning" applicable to this article?

Thanks for your feedback.
DNA replication
Is the Subject Area "DNA replication" applicable to this article?

Thanks for your feedback.
Blastocysts
Is the Subject Area "Blastocysts" applicable to this article?

Thanks for your feedback.