Intranasal Immunization with Recombinant HA and Mast Cell Activator C48/80 Elicits Protective Immunity against 2009 Pandemic H1N1 Influenza in Mice

Shu Meng; Zhonghua Liu; Lili Xu; Li Li; Shan Mei; Linlin Bao; Wei Deng; Lina Li; Rongyue Lei; Liangzhi Xie; Chuan Qin; Linqi Zhang

doi:10.1371/journal.pone.0019863

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Open Access

Peer-reviewed

Research Article

Intranasal Immunization with Recombinant HA and Mast Cell Activator C48/80 Elicits Protective Immunity against 2009 Pandemic H1N1 Influenza in Mice

Shu Meng ,

Contributed equally to this work with: Shu Meng, Zhonghua Liu

Affiliation AIDS Research Center, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Zhonghua Liu ,

Contributed equally to this work with: Shu Meng, Zhonghua Liu

Affiliation AIDS Research Center, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Lili Xu,

Affiliation Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences and Comparative Medicine Center, Peking Union Medical College, Beijing, China
⨯
Li Li,

Affiliation AIDS Research Center, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Shan Mei,

Affiliation AIDS Research Center, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Linlin Bao,

Affiliation Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences and Comparative Medicine Center, Peking Union Medical College, Beijing, China
⨯
Wei Deng,

Affiliation Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences and Comparative Medicine Center, Peking Union Medical College, Beijing, China
⨯
Lina Li,

Affiliation AIDS Research Center, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Rongyue Lei,

Affiliation AIDS Research Center, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Liangzhi Xie,

Affiliation Sino Biological Inc., Beijing, China
⨯
Chuan Qin,

Affiliation Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences and Comparative Medicine Center, Peking Union Medical College, Beijing, China
⨯
Linqi Zhang

* E-mail: zhanglinqi@tsinghua.edu.cn

Affiliations AIDS Research Center, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, Comprehensive AIDS Research Center, School of Medicine, Tsinghua University, Beijing, China
⨯

Intranasal Immunization with Recombinant HA and Mast Cell Activator C48/80 Elicits Protective Immunity against 2009 Pandemic H1N1 Influenza in Mice

Shu Meng,
Zhonghua Liu,
Lili Xu,
Li Li,
Shan Mei,
Linlin Bao,
Wei Deng,
Lina Li,
Rongyue Lei,
Liangzhi Xie

Published: May 20, 2011
https://doi.org/10.1371/journal.pone.0019863

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