Characterization of a Human Antibody Fragment Fab and Its Calcium Phosphate Nanoparticles that Inhibit Rabies Virus Infection with Vaccine

Xinjian Liu; Hong Lin; Qi Tang; Chen Li; Songtao Yang; Zhongcan Wang; Changjun Wang; Qing He; Brian Cao; Zhenqing Feng; Xiaohong Guan; Jin Zhu

doi:10.1371/journal.pone.0019848

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Open Access

Peer-reviewed

Research Article

Characterization of a Human Antibody Fragment Fab and Its Calcium Phosphate Nanoparticles that Inhibit Rabies Virus Infection with Vaccine

Xinjian Liu ,

Contributed equally to this work with: Xinjian Liu, Hong Lin

Affiliations Key Laboratory of Antibody Technique of Ministry of Health, Nanjing Medical University, Nanjing, China, Department of Pathology, Nanjing Medical University, Nanjing, China
⨯
Hong Lin ,

Contributed equally to this work with: Xinjian Liu, Hong Lin

Affiliations Key Laboratory of Antibody Technique of Ministry of Health, Nanjing Medical University, Nanjing, China, Van Andel Institute, Antibody Technology Lab, Grand Rapids, Michigan, United States of America
⨯
Qi Tang,

Affiliation Key Laboratory of Antibody Technique of Ministry of Health, Nanjing Medical University, Nanjing, China
⨯
Chen Li,

Affiliation Key Laboratory of Antibody Technique of Ministry of Health, Nanjing Medical University, Nanjing, China
⨯
Songtao Yang,

Affiliation Veterinary Institute of the Academy of Military Medical Sciences, Changchun, China
⨯
Zhongcan Wang,

Affiliation Huadong Medical Institute of Biotechniques, Nanjing, China
⨯
Changjun Wang,

Affiliation Huadong Medical Institute of Biotechniques, Nanjing, China
⨯
Qing He,

Affiliation Key Laboratory of Antibody Technique of Ministry of Health, Nanjing Medical University, Nanjing, China
⨯
Brian Cao,

Affiliation Van Andel Institute, Antibody Technology Lab, Grand Rapids, Michigan, United States of America
⨯
Zhenqing Feng,

Affiliation Key Laboratory of Antibody Technique of Ministry of Health, Nanjing Medical University, Nanjing, China
⨯
Xiaohong Guan ,

* E-mail: xiaohongguan1@163.com (XG); zjsimmons@yahoo.com.cn (JZ)

Affiliation Key Laboratory of Antibody Technique of Ministry of Health, Nanjing Medical University, Nanjing, China
⨯
Jin Zhu

* E-mail: xiaohongguan1@163.com (XG); zjsimmons@yahoo.com.cn (JZ)

Affiliations Key Laboratory of Antibody Technique of Ministry of Health, Nanjing Medical University, Nanjing, China, Huadong Medical Institute of Biotechniques, Nanjing, China
⨯

Characterization of a Human Antibody Fragment Fab and Its Calcium Phosphate Nanoparticles that Inhibit Rabies Virus Infection with Vaccine

Xinjian Liu,
Hong Lin,
Qi Tang,
Chen Li,
Songtao Yang,
Zhongcan Wang,
Changjun Wang,
Qing He,
Brian Cao,
Zhenqing Feng

Published: May 9, 2011
https://doi.org/10.1371/journal.pone.0019848

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