HMGB1 Attenuates Cardiac Remodelling in the Failing Heart via Enhanced Cardiac Regeneration and miR-206-Mediated Inhibition of TIMP-3

Federica Limana; Grazia Esposito; Daniela D'Arcangelo; Anna Di Carlo; Sveva Romani; Guido Melillo; Antonella Mangoni; Chiara Bertolami; Giulio Pompilio; Antonia Germani; Maurizio C. Capogrossi

doi:10.1371/journal.pone.0019845

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Peer-reviewed

Research Article

HMGB1 Attenuates Cardiac Remodelling in the Failing Heart via Enhanced Cardiac Regeneration and miR-206-Mediated Inhibition of TIMP-3

Federica Limana ,

Contributed equally to this work with: Federica Limana, Grazia Esposito

Affiliation Laboratorio di Biologia Vascolare e Medicina Rigenerativa, Centro Cardiologico Monzino-Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy
⨯
Grazia Esposito ,

Contributed equally to this work with: Federica Limana, Grazia Esposito

Affiliation Laboratorio di Patologia Vascolare, Istituto Dermopatico dell'Immacolata-IRCCS, Rome, Italy
⨯
Daniela D'Arcangelo,

Affiliation Laboratorio di Patologia Vascolare, Istituto Dermopatico dell'Immacolata-IRCCS, Rome, Italy
⨯
Anna Di Carlo,

Affiliation Laboratorio di Patologia Vascolare, Istituto Dermopatico dell'Immacolata-IRCCS, Rome, Italy
⨯
Sveva Romani,

Affiliation Mendel Laboratory, Casa Sollievo della Sofferenza-IRCCS, San Giovanni Rotondo, Italy
⨯
Guido Melillo,

Affiliation Laboratorio di Patologia Vascolare, Istituto Dermopatico dell'Immacolata-IRCCS, Rome, Italy
⨯
Antonella Mangoni,

Affiliation Laboratorio di Patologia Vascolare, Istituto Dermopatico dell'Immacolata-IRCCS, Rome, Italy
⨯
Chiara Bertolami,

Affiliation Laboratorio di Patologia Vascolare, Istituto Dermopatico dell'Immacolata-IRCCS, Rome, Italy
⨯
Giulio Pompilio,

Affiliation Laboratorio di Biologia Vascolare e Medicina Rigenerativa, Centro Cardiologico Monzino-Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy
⨯
Antonia Germani,

Affiliation Fondazione Livio Patrizi, Rome, Italy
⨯
Maurizio C. Capogrossi

* E-mail: capogrossi@idi.it

Affiliation Laboratorio di Patologia Vascolare, Istituto Dermopatico dell'Immacolata-IRCCS, Rome, Italy
⨯

HMGB1 Attenuates Cardiac Remodelling in the Failing Heart via Enhanced Cardiac Regeneration and miR-206-Mediated Inhibition of TIMP-3

Federica Limana,
Grazia Esposito,
Daniela D'Arcangelo,
Anna Di Carlo,
Sveva Romani,
Guido Melillo,
Antonella Mangoni,
Chiara Bertolami,
Giulio Pompilio,
Antonia Germani

Published: June 22, 2011
https://doi.org/10.1371/journal.pone.0019845

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