miR-346 Controls Release of TNF-α Protein and Stability of Its mRNA in Rheumatoid Arthritis via Tristetraprolin Stabilization

Noha Semaan; Laurent Frenzel; Ghada Alsaleh; Guillaume Suffert; Jacques-Eric Gottenberg; Jean Sibilia; Sebastien Pfeffer; Dominique Wachsmann

doi:10.1371/journal.pone.0019827

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Peer-reviewed

Research Article

miR-346 Controls Release of TNF-α Protein and Stability of Its mRNA in Rheumatoid Arthritis via Tristetraprolin Stabilization

Noha Semaan ,

Contributed equally to this work with: Noha Semaan, Laurent Frenzel

Affiliation Laboratoire Physiopathologie des Arthrites, EA4438, Université de Strasbourg, UFR Sciences Pharmaceutiques, Illkirch, France and Departement de Rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg Hautepierre, France
⨯
Laurent Frenzel ,

Contributed equally to this work with: Noha Semaan, Laurent Frenzel

Affiliation Laboratoire Physiopathologie des Arthrites, EA4438, Université de Strasbourg, UFR Sciences Pharmaceutiques, Illkirch, France and Departement de Rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg Hautepierre, France
⨯
Ghada Alsaleh,

Affiliation Laboratoire Physiopathologie des Arthrites, EA4438, Université de Strasbourg, UFR Sciences Pharmaceutiques, Illkirch, France and Departement de Rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg Hautepierre, France
⨯
Guillaume Suffert,

Affiliation Architecture et Réactivité de l'ARN, Université de Strasbourg, Institut de Biologie Moléculaire et Cellulaire du CNRS, Strasbourg, France
⨯
Jacques-Eric Gottenberg,

Affiliation Laboratoire Physiopathologie des Arthrites, EA4438, Université de Strasbourg, UFR Sciences Pharmaceutiques, Illkirch, France and Departement de Rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg Hautepierre, France
⨯
Jean Sibilia,

Affiliation Laboratoire Physiopathologie des Arthrites, EA4438, Université de Strasbourg, UFR Sciences Pharmaceutiques, Illkirch, France and Departement de Rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg Hautepierre, France
⨯
Sebastien Pfeffer ,

* E-mail: s.pfeffer@ibmc-cnrs.unistra.fr (SP); dominique.wachsmann@pharma.u-strasbg.fr (DW)

Affiliation Architecture et Réactivité de l'ARN, Université de Strasbourg, Institut de Biologie Moléculaire et Cellulaire du CNRS, Strasbourg, France
⨯
Dominique Wachsmann

* E-mail: s.pfeffer@ibmc-cnrs.unistra.fr (SP); dominique.wachsmann@pharma.u-strasbg.fr (DW)

Affiliation Laboratoire Physiopathologie des Arthrites, EA4438, Université de Strasbourg, UFR Sciences Pharmaceutiques, Illkirch, France and Departement de Rhumatologie, Hôpitaux Universitaires de Strasbourg, Strasbourg Hautepierre, France
⨯

miR-346 Controls Release of TNF-α Protein and Stability of Its mRNA in Rheumatoid Arthritis via Tristetraprolin Stabilization

Noha Semaan,
Laurent Frenzel,
Ghada Alsaleh,
Guillaume Suffert,
Jacques-Eric Gottenberg,
Jean Sibilia,
Sebastien Pfeffer,
Dominique Wachsmann

Published: May 17, 2011
https://doi.org/10.1371/journal.pone.0019827

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