UMP/CMPK Is Not the Critical Enzyme in the Metabolism of Pyrimidine Ribonucleotide and Activation of Deoxycytidine Analogs in Human RKO Cells

Open Access

Peer-reviewed

Research Article

Rong Hu,

Affiliation Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Wing Lam,

Affiliation Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Chih-Hung Hsu,

Affiliations Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan, Republic of China
⨯
Yung-Chi Cheng

* E-mail: yccheng@yale.edu

Affiliations Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan, Republic of China
⨯

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Cell metabolism
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Doxycycline
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Enzyme metabolism
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Protein metabolism
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Pyrimidines
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In vitro kinase assay
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Nucleotides
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Enzymes
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