Altered mRNA Editing and Expression of Ionotropic Glutamate Receptors after Kainic Acid Exposure in Cyclooxygenase-2 Deficient Mice

Luca Caracciolo; Alessandro Barbon; Sara Palumbo; Cristina Mora; Christopher D. Toscano; Francesca Bosetti; Sergio Barlati

doi:10.1371/journal.pone.0019398

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Peer-reviewed

Research Article

Altered mRNA Editing and Expression of Ionotropic Glutamate Receptors after Kainic Acid Exposure in Cyclooxygenase-2 Deficient Mice

Luca Caracciolo,

Affiliations Molecular Neuroscience Unit, Brain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America, Division of Biology and Genetics, Department of Biomedical Sciences and Biotechnologies and National Institute of Neuroscience, University of Brescia, Brescia, Italy
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Alessandro Barbon,

Affiliation Division of Biology and Genetics, Department of Biomedical Sciences and Biotechnologies and National Institute of Neuroscience, University of Brescia, Brescia, Italy
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Sara Palumbo,

Affiliation Molecular Neuroscience Unit, Brain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America
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Cristina Mora,

Affiliation Division of Biology and Genetics, Department of Biomedical Sciences and Biotechnologies and National Institute of Neuroscience, University of Brescia, Brescia, Italy
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Christopher D. Toscano,

Affiliation Molecular Neuroscience Unit, Brain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America
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Francesca Bosetti ,

* E-mail: frances@mail.nih.gov

Current address: National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

Affiliation Molecular Neuroscience Unit, Brain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America
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Sergio Barlati

Affiliation Division of Biology and Genetics, Department of Biomedical Sciences and Biotechnologies and National Institute of Neuroscience, University of Brescia, Brescia, Italy
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Altered mRNA Editing and Expression of Ionotropic Glutamate Receptors after Kainic Acid Exposure in Cyclooxygenase-2 Deficient Mice

Luca Caracciolo,
Alessandro Barbon,
Sara Palumbo,
Cristina Mora,
Christopher D. Toscano,
Francesca Bosetti,
Sergio Barlati

Published: May 12, 2011
https://doi.org/10.1371/journal.pone.0019398

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Hippocampus
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Glutamate
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Gene expression
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RNA editing
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Messenger RNA
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Analysis of variance
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Ligand-gated ion channels
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Neuronal death
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