Specificity of Mimotope-Induced Anti-High Molecular Weight-Melanoma Associated Antigen (HMW-MAA) Antibodies Does Not Ensure Biological Activity

Julia Latzka; Sonja Gaier; Gerlinde Hofstetter; Nina Balazs; Ursula Smole; Soldano Ferrone; Otto Scheiner; Heimo Breiteneder; Hubert Pehamberger; Stefan Wagner

doi:10.1371/journal.pone.0019383

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Open Access

Peer-reviewed

Research Article

Specificity of Mimotope-Induced Anti-High Molecular Weight-Melanoma Associated Antigen (HMW-MAA) Antibodies Does Not Ensure Biological Activity

Julia Latzka ,

Contributed equally to this work with: Julia Latzka, Sonja Gaier

Affiliation Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria
⨯
Sonja Gaier ,

Contributed equally to this work with: Julia Latzka, Sonja Gaier

Affiliation Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria
⨯
Gerlinde Hofstetter,

Affiliation Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria
⨯
Nina Balazs,

Affiliation Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria
⨯
Ursula Smole,

Affiliation Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria
⨯
Soldano Ferrone,

Affiliation Department of Surgery, of Immunology and of Pathology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America
⨯
Otto Scheiner,

Affiliation Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria
⨯
Heimo Breiteneder,

Affiliation Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria
⨯
Hubert Pehamberger,

Affiliation Division of General Dermatology, Department of Dermatology, Medical University of Vienna, Vienna, Austria
⨯
Stefan Wagner

* E-mail: stefan.wagner@meduniwien.ac.at

Affiliation Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria
⨯

Specificity of Mimotope-Induced Anti-High Molecular Weight-Melanoma Associated Antigen (HMW-MAA) Antibodies Does Not Ensure Biological Activity

Julia Latzka,
Sonja Gaier,
Gerlinde Hofstetter,
Nina Balazs,
Ursula Smole,
Soldano Ferrone,
Otto Scheiner,
Heimo Breiteneder,
Hubert Pehamberger,
Stefan Wagner

Published: May 6, 2011
https://doi.org/10.1371/journal.pone.0019383

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