An ENU-Mutagenesis Screen in the Mouse: Identification of Novel Developmental Gene Functions

Carolien Wansleeben; Léon van Gurp; Harma Feitsma; Carla Kroon; Ester Rieter; Marlies Verberne; Victor Guryev; Edwin Cuppen; Frits Meijlink

doi:10.1371/journal.pone.0019357

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Open Access

Peer-reviewed

Research Article

An ENU-Mutagenesis Screen in the Mouse: Identification of Novel Developmental Gene Functions

Carolien Wansleeben,

Current address: Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, United States of America

Affiliation Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, Utrecht, The Netherlands
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Léon van Gurp,

Affiliation Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Harma Feitsma,

Current address: Philips Research Labs, Eindhoven, The Netherlands

Affiliation Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Carla Kroon,

Affiliation Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Ester Rieter,

Current address: Department of Cell Biology and Institute of Biomembranes, University Medical Centre Utrecht, Utrecht, The Netherlands

Affiliation Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Marlies Verberne,

Affiliation Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Victor Guryev,

Affiliation Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Edwin Cuppen,

Affiliation Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Frits Meijlink

* E-mail: f.meijlink@hubrecht.eu

Affiliation Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯

An ENU-Mutagenesis Screen in the Mouse: Identification of Novel Developmental Gene Functions

Carolien Wansleeben,
Léon van Gurp,
Harma Feitsma,
Carla Kroon,
Ester Rieter,
Marlies Verberne,
Victor Guryev,
Edwin Cuppen,
Frits Meijlink

Published: April 29, 2011
https://doi.org/10.1371/journal.pone.0019357

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10 Jun 2011
08:25 GMT
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Update from authors Posted by fmeijlink on 10 Jun 2011 at 08:25 GMT

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Phenotypes
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Edema
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Lung development
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Substitution mutation
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Single nucleotide polymorphisms
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Gene identification and analysis
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