The Phosphodiesterase-5 Inhibitor Vardenafil Is a Potent Inhibitor of ABCB1/P-Glycoprotein Transporter

• Pei-Rong Ding,

  Affiliations Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, New York, United States of America, State Key Laboratory of Oncology in South China, Cancer Center, Sun Yat-Sen University, Guangzhou, China, Department of Colorectal Surgery, Cancer Center, Sun Yat-Sen University, Guangzhou, China

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• Amit K. Tiwari,

  Affiliation Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, New York, United States of America

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• Shinobu Ohnuma,

  Affiliation Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Jeferson W. K. K. Lee,

  Affiliation Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, New York, United States of America

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• Xin An,

  Affiliations Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, New York, United States of America, State Key Laboratory of Oncology in South China, Cancer Center, Sun Yat-Sen University, Guangzhou, China, Department of Medical Oncology, Cancer Center, Sun Yat-Sen University, Guangzhou, China

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• Chun-Ling Dai,

  Affiliation Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, New York, United States of America

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• Qi-Si Lu,

  Current address: Southern Medical University, Guangzhou, China

  Affiliation Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, New York, United States of America

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• Satyakam Singh,

  Affiliation Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, New York, United States of America

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• Dong-Hua Yang,

  Affiliation Biosample Repository, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America

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• Tanaji T. Talele,

  Affiliation Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, New York, United States of America

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• Suresh V. Ambudkar,

  Affiliation Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Zhe-Sheng Chen

  * E-mail: Chenz@stjohns.edu

  Affiliation Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, New York, United States of America

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