Mastering the Canonical Loop of Serine Protease Inhibitors: Enhancing Potency by Optimising the Internal Hydrogen Bond Network

• Joakim E. Swedberg,

  Affiliation Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia

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• Simon J. de Veer,

  Affiliation Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia

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• Kei C. Sit,

  Affiliation Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia

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• Cyril F. Reboul,

  Affiliation Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Faculty of Medicine and Victorian Bioinformatics Consortium, Monash University, Clayton, Victoria, Australia

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• Ashley M. Buckle,

  Affiliation Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Faculty of Medicine and Victorian Bioinformatics Consortium, Monash University, Clayton, Victoria, Australia

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• Jonathan M. Harris

  * E-mail: j2.harris@qut.edu.au

  Affiliation Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia

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