Excessive Biologic Response to IFNβ Is Associated with Poor Treatment Response in Patients with Multiple Sclerosis

• Richard A. Rudick ,

  Contributed equally to this work with: Richard A. Rudick, Richard M. Ransohoff

  * E-mail: rudickr@ccf.org

  Affiliation Mellen Center for Multiple Sclerosis, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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• M. R. Sandhya Rani,

  Affiliation Department of Neurosciences, Neuroinflammation Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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• Yaomin Xu,

  Affiliation Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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• Jar-Chi Lee,

  Affiliation Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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• Jie Na,

  Affiliation Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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• Jennifer Shrock,

  Affiliation Department of Neurosciences, Neuroinflammation Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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• Anupama Josyula,

  Affiliation Department of Neurosciences, Neuroinflammation Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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• Elizabeth Fisher,

  Affiliation Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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• Richard M. Ransohoff

  Contributed equally to this work with: Richard A. Rudick, Richard M. Ransohoff

  Affiliations Mellen Center for Multiple Sclerosis, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Department of Neurosciences, Neuroinflammation Research Center, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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