The Expression of VEGF-A Is Down Regulated in Peripheral Blood Mononuclear Cells of Patients with Secondary Progressive Multiple Sclerosis

Ellen Iacobaeus; Petra Amoudruz; Mikael Ström; Mohsen Khademi; Lou Brundin; Jan Hillert; Ingrid Kockum; Vivianne Malmström; Tomas Olsson; Emma Tham; Fredrik Piehl

doi:10.1371/journal.pone.0019138

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Open Access

Peer-reviewed

Research Article

The Expression of VEGF-A Is Down Regulated in Peripheral Blood Mononuclear Cells of Patients with Secondary Progressive Multiple Sclerosis

Ellen Iacobaeus ,

* E-mail: Ellen.Iacobaeus@karolinska.se

Affiliation Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institute Solna, Center for Molecular Medicine, Stockholm, Sweden
⨯
Petra Amoudruz ,

Contributed equally to this work with: Petra Amoudruz, Mikael Ström

Affiliation Department of Medicine, Rheumatology Unit, Karolinska Institute Solna, Center for Molecular Medicine, Stockholm, Sweden
⨯
Mikael Ström ,

Contributed equally to this work with: Petra Amoudruz, Mikael Ström

Affiliation Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institute Solna, Center for Molecular Medicine, Stockholm, Sweden
⨯
Mohsen Khademi,

Affiliation Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institute Solna, Center for Molecular Medicine, Stockholm, Sweden
⨯
Lou Brundin,

Affiliation Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institute Solna, Center for Molecular Medicine, Stockholm, Sweden
⨯
Jan Hillert,

Affiliation Department of Clinical Neuroscience, The Multiple Sclerosis Research Group, Karolinska Institute Solna, Center for Molecular Medicine, Stockholm, Sweden
⨯
Ingrid Kockum,

Affiliation Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institute Solna, Center for Molecular Medicine, Stockholm, Sweden
⨯
Vivianne Malmström,

Affiliation Department of Medicine, Rheumatology Unit, Karolinska Institute Solna, Center for Molecular Medicine, Stockholm, Sweden
⨯
Tomas Olsson,

Affiliation Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institute Solna, Center for Molecular Medicine, Stockholm, Sweden
⨯
Emma Tham,

Affiliation Department of Clinical Genetics, L5:03, Karolinska University Hospital, Solna, Sweden
⨯
Fredrik Piehl

Affiliation Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institute Solna, Center for Molecular Medicine, Stockholm, Sweden
⨯

The Expression of VEGF-A Is Down Regulated in Peripheral Blood Mononuclear Cells of Patients with Secondary Progressive Multiple Sclerosis

Ellen Iacobaeus,
Petra Amoudruz,
Mikael Ström,
Mohsen Khademi,
Lou Brundin,
Jan Hillert,
Ingrid Kockum,
Vivianne Malmström,
Tomas Olsson,
Emma Tham

Published: May 6, 2011
https://doi.org/10.1371/journal.pone.0019138

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Multiple sclerosis
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Monocytes
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Cerebrospinal fluid
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Medical risk factors
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Gene expression
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Single nucleotide polymorphisms
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Blood
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Amyotrophic lateral sclerosis
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